Publications by authors named "Edmund Drage"
Idiopathic pulmonary arterial hypertension is a rare and life-shortening condition often diagnosed at an advanced stage. Despite increased awareness, the delay to diagnosis remains unchanged. This study explores whether a predictive model based on healthcare resource utilisation can be used to screen large populations to identify patients at high risk of idiopathic pulmonary arterial hypertension.
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- Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is a serious cause of heart failure in older adults, with significant diagnostic delays often leading to poor quality of life before diagnosis.* -
- The study analyzed 1,034 patients over several years, revealing that those with hereditary forms of the disease (specifically the V1221 variant) experienced greater functional impairment and worse outcomes compared to those with the wild-type form.* -
- Urgent improvements in awareness and diagnostic methods are necessary to facilitate earlier diagnosis and treatment, as ATTR-CM is a progressively fatal disease that severely impacts patients' quality of life.*
Idiopathic pulmonary arterial hypertension (iPAH) is a rare progressive, life-shortening disease, usually diagnosed at an advanced stage. We hypothesize that patients with iPAH exhibit patterns of health-seeking behavior before diagnosis that will allow the development of earlier identification tools. The Sheffield Pulmonary Hypertension IndeX (SPHInX) project aims to develop a predictive algorithm based on routinely collected healthcare resource utilization (HCRU) data.
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