Publications by authors named "Edmund C L Cheung"

Introduction And Objective: The risk of seizure in offspring following prenatal exposure to levothyroxine is not well investigated. This study aimed to evaluate the association between levothyroxine treatment among pregnant women and the risk of seizure in their offspring.

Methods: This population-based cohort study included all pregnant women who delivered a live birth between January 2001 to January 2018, with a follow-up to December 2020, using data from the Hong Kong Clinical Data Analysis and Reporting System.

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Objectives: The aim of this study was to compare incidences of adverse events of special interest (AESI) and delirium in 3 cohorts: after COVID-19 vaccination, prepandemic, and SARS-CoV-2 polymerase chain reaction (PCR) test positive.

Design: This is a population-based cohort study using electronic medical records linked with vaccination records in Hong Kong.

Setting And Participants: A total of 17,449 older people with dementia received at least 1 dose of CoronaVac (n = 14,719) or BNT162b2 (n = 2730) between February 23, 2021, and March 31, 2022.

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Article Synopsis
  • The study analyzed benzodiazepine (BZD) and Z-drug consumption trends from 2008 to 2018 across 67 countries using pharmaceutical sales data.
  • BZD usage decreased by 1.88% yearly, while Z-drug use rose by 3.28%, with European countries showing the highest consumption levels.
  • Higher usage rates were linked to increased GDP and the prevalence of various medical conditions, indicating a need for more research on the safety and implications of BZD and Z-drug use, particularly in patients with existing health issues.
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Background: The influence of maternal levothyroxine treatment during pregnancy remains unclear. This study aimed to evaluate the associations of maternal levothyroxine treatment during pregnancy with the birth and neurodevelopmental outcomes in offspring.

Methods: This population-based cohort study was conducted among pregnant women using the Hong Kong Clinical Data Analysis and Reporting System.

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Background: Age-specific incidence of acute myocarditis/pericarditis in adolescents following Comirnaty vaccination in Asia is lacking. This study aimed to study the clinical characteristics and incidence of acute myocarditis/pericarditis among Hong Kong adolescents following Comirnaty vaccination.

Methods: This is a population cohort study in Hong Kong that monitored adverse events following immunization through a pharmacovigilance system for coronavirus disease 2019 (COVID-19) vaccines.

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