Publications by authors named "Edmund Baracat"

Objective: To test the Intra- and inter-rater reliability, measurement error and criteria and convergent validities of the Dualpex Plus (DP) for vaginal manometry in women with urinary incontinence (UI).

Design: This is a clinimetric properties study.

Setting: University Hospital in Brazil.

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Article Synopsis
  • The study aimed to compare three assessment methods for pelvic floor function—PERFECT scheme, vaginal manometry, and transperineal ultrasound—in women with and without stress urinary incontinence (SUI).
  • It involved a cross-sectional analysis of 51 women with SUI and 47 without, evaluating various pelvic floor metrics while excluding those with severe conditions.
  • Results showed strong correlations among some measures of the PERFECT scheme and vaginal manometry in the SUI group, but no correlation between ultrasound variables and the other assessment methods.
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Background: Ovarian cryopreservation is a promising technique despite being hindered by damage from freezing and thawing. Melatonin can mitigate this outcome.

Objective: This study aimed to evaluate the effect of melatonin on the follicular dynamics of ovarian tissue in a cryopreserved cell culture.

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Background: Brazil faces notable Breast Cancer (BC) mortality despite lower incidence rates versus developed countries. Despite guidelines from medical societies, Brazilian public policy recommends biennial mammographic screening for women aged 50 to 69. This study investigates sociodemographic and clinical factors related to BC detection methods and clinical stage at diagnosis.

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Introduction: Uterine transplantation was developed for the treatment of absolute uterine factor infertility. As it is a new modality of transplantation, there is still room for technical improvement. A factor that impacts graft survival in organ transplantation is the warm ischemia time.

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  • The study explores the link between knee muscle strength, postural balance, and mobility in older women, aiming to identify fall risks and improve prevention programs.
  • Results showed that higher knee strength correlates with better functional mobility but only weakly relates to semi-static balance, indicating different coordination requirements for each activity.
  • Overall, findings suggest that improving knee strength can enhance mobility in elderly women, while maintaining balance may rely on different neuromuscular controls.
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Objectives: To validate probe-based Confocal Laser Endomicroscopy (pCLE) as a method in assessing endometriosis during conventional and robot-assisted laparoscopy.

Study Design: Pilot study, including five women in Hospital Moriah, São Paulo, Brazil. During laparoscopic procedures, pCLE was used to assess endometriosis lesions, complemented by subsequent histological evaluations.

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The social isolation imposed by the COVID-19 pandemic interrupted in-person activities, which were immediately followed by adaptations to ensure, for example, the continuity of teaching. This generated emotional impacts on the academic community. Emotional states may trigger or emphasize conditions such as temporomandibular dysfunction (TMD), causing pain and limiting masticatory function.

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Purpose: To assess the association between tumor-infiltrating lymphocytes (TILs) in ductal carcinoma in situ (DCIS) samples and disease recurrence.

Methods: This retrospective cohort study included women aged 18 years and older who underwent treatment between January 2007 and December 2020. Male patients, individuals diagnosed with invasive or microinvasive disease based on anatomopathological examination of surgical specimens, and those with a personal history of any other cancers were excluded.

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  • The study aimed to assess the effectiveness of cognitive behavioral therapy (CBT) for treating vasomotor symptoms, sexual dysfunction, and recurrent depression in postmenopausal women.
  • It involved 112 participants divided into two groups: one without depression and one with recurrent depression, both receiving therapy sessions over six months.
  • Results showed significant improvements in both groups' symptoms after 24 weeks of treatment, although the improvements in the group with depression diminished after 48 weeks.
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Introduction And Hypothesis: Condition-specific sexual questionnaires are important patient-reported outcome measures. The aim of this study was to translate and validate the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-International Urogynecology Association Revised (PISQ-IR) into Brazilian Portuguese and to clinically validate it in a Brazilian Portuguese-speaking population.

Methods: Translation and validation of the PISQ-IR was performed according to the International Urogynecological Association-recommended process and guidelines.

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Gender relations are a set of socially determined norms and rules that assign values, characteristics, and expectations to individuals based on their biological sex. These aspects also influence the clinician-patient relationship, since it has been for a long time based on cisheteronormativity. However, this attitude alienated the LGBTQIA+ community from health services.

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Background: Polycystic ovary syndrome (PCOS) is a heterogenous endocrine condition and combined oral contraceptives (COCs) have been demonstrated to be the first-line treatment to women who do not intend to become pregnant. The combination of COCs and PCOS may or may not amplify the risks of cardiovascular events.

Objective: To investigate whether surrogates for obesity may be influenced by the use of COCs containing different formulations in women with PCOS.

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Background: Melatonin is a hormone produced by the pineal gland and it has antioxidant properties.

Aim: This study aimed to evaluate the effects of melatonin on assisted reproductive technologies through a systematic review and a meta-analysis.

Materials And Methods: Search strategies were used in PubMed and in other databases covering the last 15 years.

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Context: Vehicle driving depends on the integration of motor, visual, and cognitive skills to respond appropriately to different situations that occur in traffic.

Objectives: To analyze a model of performance predictor for braking time in the driving simulator, using a battery of tests divided by gender.

Methods: Selected were 100 male drivers with a mean age of 72.

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Objective: To analyze differences in the menstrual pattern, age at menarche, and body mass index (BMI) in adolescents with Hypothalamic-Pituitary-Ovarian (HPO) axis immaturity and Polycystic Ovary Syndrome (PCOS) through a systematic review and meta-analysis.

Methods: The PubMed, EMBASE, Web of Science, Virtual Health Library, Scopus databases were searched using combinations of descriptors. Study quality was assessed using the Newcastle-Ottawa Scale.

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Introduction: An accurate assessment of balance problems is critical for decreasing the risk of falling in patients with Parkinson's Disease (PD). Reliable diagnostic tools such as Computerized Dynamic Posturography (CDP) are not feasible for the clinical setting. Therefore, the present study's aim was to assess the correlation between the clinical Balance Evaluation Systems Test (BESTest) and CDP.

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Objective: To compare the effects of fractional CO2 laser and microablative fractional radiofrequency treatment with promestriene topical estrogen on sexual function and genitourinary syndrome of menopause symptoms.

Methods: This was a prospective randomized open-label clinical trial conducted with 62 postmenopausal women assigned to three intervention groups: a) topical promestriene for 90 days (n = 17); b) fractional CO2 laser treatment (n = 24); and c) microablative fractional radiofrequency treatment (n = 21). Each of the latter two groups underwent three treatment sessions at 4-week intervals.

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Unlabelled: Melatonin is an indoleamine with crucial antioxidant properties that are used to combat inflammatory and neoplastic processes, as well as control transplants. However, the clinical applications of melatonin have not yet been fully consolidated in the literature and require in-depth analysis.

Objectives: This study reviewed the literature on the antioxidant properties of melatonin in rat models.

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Objective: The present study aimed to investigate FOXO3a deregulation in Uterine Smooth Muscle Tumors (USMT) and its potential association with cancer development and prognosis.

Methods: The authors analyzed gene and protein expression profiles of FOXO3a in 56 uterine Leiomyosarcomas (LMS), 119 leiomyomas (comprising conventional and unusual leiomyomas), and 20 Myometrium (MM) samples. The authors used techniques such as Immunohistochemistry (IHC), FISH/CISH, and qRT-PCR for the present analyses.

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Article Synopsis
  • The study aimed to assess the impact of estrogen, raloxifene, and genistein on certain gene expressions related to bone health in ovariectomized rats.
  • Forty-eight adult rats were divided into six groups for different treatments over a period of 120 days, with assessments done post-treatment for gene expression in the tibia.
  • Results showed that raloxifene, either alone or with estrogen, increased gene expression linked to bone health, while other treatments indicated decreased expression, suggesting raloxifene’s effectiveness in restoring bone tissue balance.
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