Enhancing Genetic Medicine: Rapid and Cost-Effective Molecular Diagnosis for a Founder Mutation for Hearing Impairment in Ghana.

In Ghana, gap-junction protein β 2 () variants account for about 25.9% of familial hearing impairment (HI) cases. The -p.

and Mutations in Hereditary Recessive Non-Syndromic Hearing Impairment in Cameroon.

This study aimed to investigate (connexin 26) and (connexin 30) mutations associated with familial non-syndromic childhood hearing impairment (HI) in Cameroon. We selected only families segregating HI, with at least two affected individuals and with strong evidence of non-environmental causes. DNA was extracted from peripheral blood, and the entire coding region of was interrogated using Sanger sequencing.