Online Screening and Virtual Patient Education for Hereditary Cancer Risk Assessment and Testing.

Objective: To use online screening and virtual patient education tools to improve the provision of hereditary cancer risk assessment.

Methods: We conducted a prospective, single-arm study in which clinicians at five U.S.

Genetic cancer risk assessment for PA practice.

The roles of cancer genetics and risk assessment as areas of medicine are rapidly evolving. Genetic cancer risk assessment (GCRA) has begun to penetrate patient care for providers in all specialties and areas of expertise. To provide comprehensive patient care and thorough risk evaluation, physician associates/assistants (PAs) should have a fundamental understanding of the role of GCRA as it pertains to their patients' overall health and medical management.

Breast Cancer Prognostic Tests: Helping Patients Understand Testing Results and Their Implications.

Breast cancer prognostic tests have become an essential component of breast cancer care. Oncology nurses play an important role in assisting patients in their understanding of and decision making regarding the use of prognostic tests in treatment planning. This article outlines the most commonly used breast cancer prognostic tests, including the individual assay's purpose, its genomic makeup, the targeted patient population, and its prognostic and predictive abilities.

PALB2 and the risks for cancer: implications for clinical care.

Mutations in the PALB2 gene are responsible for a small but significant percentage of cancer risks in familial breast and pancreatic cancer families. PALB2 mutations may be associated with an increase in other cancer risks as well. This article will provide an overview of the PALB2 gene, cancer risks associated with carrying a PALB2 mutation, and implications for patient care.

Understanding CYP2D6 and its role in tamoxifen metabolism.

The gene CYP2D6 has an extremely important role in drug metabolism. "Cytochrome P450, family 2, subfamily D, polypeptide 6" is the official name of CYP2D6. The gene is located at position 13.

An overview of hereditary breast and ovarian cancer syndrome.

Hereditary breast and ovarian cancer syndrome is an inherited condition that women's health care providers are likely to encounter in their practices. Persons affected by this disorder have extremely high risks for developing cancer. This article provides a definition and overview of the syndrome, including cancer prevention/risk reduction strategies and resources available for patients and providers.