Publications by authors named "Edit Castren"

Article Synopsis
  • * We identified key clinical variables, such as serum alkaline phosphatase levels and extrahepatic biliary disease, that strongly predict 10-year outcomes, leading to the creation of two effective risk scoring systems.
  • * Our new UK-PSC risk scores successfully predicted outcomes better than existing models, and while a specific genetic risk allele was associated with worse outcomes, it didn’t enhance the accuracy of our scores.
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Hepatic portal venous gas (HPVG) in most cases signifies either mechanical migration of air into the portal system due to bowel ischaemia (pneumatosis intestinalis) or portal sepsis due to gas-forming organisms. Successful management of portal sepsis involves early identification of the condition, intensive resuscitation, broad-spectrum antibiotics and a laparotomy for possible bowel ischaemia. In this report, we discuss the case of a patient with pneumatosis intestinalis and HPVG after an elective laparoscopic right hemicolectomy.

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