Publications by authors named "Edinara Targino de Melo"
Structural characterization of a novel peptide with antimicrobial activity from the venom gland of the scorpion Tityus stigmurus: Stigmurin.
Edinara Targino de Melo Andréia Bergamo Estrela Elizabeth Cristina Gomes Santos Paula Renata Lima Machado Kleber Juvenal Silva Farias Taffarel Melo Torres
Peptides
June 2015
Article Synopsis
- A new antimicrobial peptide called Stigmurin was identified from the venom gland of the Brazilian yellow scorpion, Tityus stigmurus, showcasing the potential of scorpion venom for biotechnological uses.
- Stigmurin's structure was analyzed through circular dichroism spectroscopy, revealing how it changes shape in membrane-like environments, indicating its interaction with cell membranes.
- The peptide demonstrated significant antibacterial and antifungal properties, along with toxicity against specific cell lines, suggesting its potential as a new anti-infective drug.