Publications by authors named "Edilson Silva Machado"
Update on Musculoskeletal Pain Management.
Rev Bras Ortop (Sao Paulo)
April 2024
Pain is the most common complaint reported to orthopedists in the outpatient clinic, emergency room, or booth. Numerous publications report the inadequate management of both acute and chronic pain by health professionals. This updated article aims to provide information about musculoskeletal pain, its classification, evaluation, diagnosis, and the multimodal therapeutic approach for each case.
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- - The study investigates the effectiveness of platelet-rich plasma (PRP) injections as a treatment for low back pain (LBP), which has significant economic impacts and is linked to spinal degeneration, particularly in intervertebral discs and facet joints.
- - A systematic review of 2324 articles identified 40 eligible studies (13 randomized clinical trials and 27 nonrandomized trials or case series) that evaluated the use of PRP, with most studies reporting positive outcomes for pain relief and improved disability.
- - While 11 out of 13 RCTs showed beneficial results, it was noted that there was a high overall risk of bias in some studies and a 72.7% compliance rate with PRP preparation descriptions, suggesting a
Objective: To describe and analyze a new protocol for the extraction of platelet-rich plasma (PRP) for use in clinical practice and compare this technique with methods that have been previously described in the medical literature.
Methods: We extracted PRP from 20 volunteers using four different protocols (single spin at 1600 ×g, single spin at 600 ×g, double spin at 300 and 700 ×g, and double spin at 600 and 900 ×g). In another group of 12 individuals, we extracted PRP with our new technique (named 'turn down-turn up') consisting of a double spin (200 ×g and 1600 ×g) closed system using standard laboratory equipment (including an ordinary benchtop centrifuge), where the blood remained in the same tube during all processes, reducing the risk of contamination.