Publications by authors named "Edila Monteiro de Andrade"
Social, Genetics and Histopathological Factors Related to () Gene Mutation and Survival in Women with Ovarian Serous Cystadenocarcinoma: Bioinformatics Analysis.
Fabiana de Campos Gomes Eric Renato Lima Figueiredo Ediane Nunes De Araújo Edila Monteiro De Andrade Carlos Diego Lisbôa Carneiro Helana Augusta Andrade Leal Dias
Genes (Basel)
May 2023
Article Synopsis
- The study explored factors that may heighten the risk of ovarian serous cystadenocarcinoma, focusing on the connection between social, genetic, and histopathological elements in women with titin mutations.
- Researchers analyzed data from 585 patient samples to determine if the mutation in the titin gene could serve as a predictor of outcomes, using statistical methods such as logistic regression and Kaplan-Meier survival analysis.
- Findings revealed that titin mutations did not vary by age, tumor stage, or race but were linked to several genetic markers and metrics related to cancer cell metabolism, revealing a significant impact on mutation frequency and survival indicators.
Article Synopsis
- The study investigated the relationship between sociodemographic and clinical factors in live births with spinal dysraphism in Brazil from 1999 to 2019.
- Notable findings included an overall increase in spinal dysraphism cases, with high incidence in mothers born after 1980, older than 30, and with higher education levels.
- The absence of prenatal care was linked to higher rates of spinal dysraphism, particularly among live births weighing less than 3000g and occurring from double pregnancies.*