Publications by authors named "Edia Filomena Di Tullio Lopes"
Article Synopsis
- - The study explored the presence of pathogenic germline variants in Brazilian patients with pancreatic adenocarcinoma, involving 192 unselected patients and analyzing 113 cancer-related genes, revealing a median age of 61 years and a significant portion presenting advanced disease stages.
- - Of the patients, 6.25% carried pathogenic variants linked to known pancreatic cancer genes, while 13% had variants in genes with less established associations, with CHEK2, ATM, and FANC being the most affected.
- - No differences in the prevalence of these variants were found based on family cancer history or ancestry, suggesting that all Brazilian pancreatic cancer patients should undergo genetic testing regardless of their background.
Clinical stage and histological type of the most common carcinomas diagnosed in young adults in a reference cancer hospital.
Marina Candido Visontai Cormedi Edia Filomena Di Tullio Lopes Simone Maistro Rosimeire Aparecida Roela Maria Aparecida Azevedo Koike Folgueira
Clinics (Sao Paulo)
September 2018
Objectives: Cancer in young adults represents a great challenge, both biologically and socially, and understanding the unique characteristics of neoplasms in this age group is important to improving care. We aimed to evaluate the most common carcinomas and their characteristics, such as histological type and clinical stage, in young adults in the largest cancer hospital in Latin America.
Methods: The hospital registry was consulted for the period between 2008 and 2014.