Publications by authors named "Edi Sukaton"
In the course to find a new whitening agent, we evaluated the methanol extract from bud of clove (Syzygium aromaticum) on melanin formation in B16 melanoma cells. Eugenol and eugenol acetate were isolated as the active compounds and showed melanin inhibition of 60% and 40% in B16 melanoma cell with less cytotoxicity at the concentration of 100 and 200 μg/mL, respectively. Furthermore, an essential oil prepared from the bud of clove, which contain eugenol and eugenol acetate as dominant components, showed melanin inhibition of 50% and 80% in B16 melanoma cells at the concentration of 100 and 200 μg/mL, respectively.
View Article and Find Full Text PDFArticle Synopsis
- Researchers studied Kleinhovia hospita leaves, traditionally used in Indonesia for liver disease, to identify their antioxidant properties.
- The leaves were extracted with methanol and further separated into different fractions, and their antioxidant activity was tested alongside cytotoxic effects on liver cancer cells (HepG2).
- The methanol extract displayed strong antioxidant activity (96%) similar to vitamin C (98%) and showed moderate cytotoxicity against HepG2 cells at varying concentrations.