Publications by authors named "Edgar Vazquez"
In this work, we developed an alternative manufacturing paper-based microfluidics method through 3D printing and wax filament. Microfluidic paper-based analytical devices (μPADs) are low-cost and easy-to-manufacture tools used for various chemical and biological analyses and studies. Paper-based microfluidics with wax has been limited as the manufacturers have discontinued most wax printing equipment.
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- Chronic exposure to arsenic (As) affects over 150 million people globally, linked to serious health issues like cancer and metabolic disorders such as type 2 diabetes and obesity.
- Researchers studied the impact of prenatal and early life As exposure on lipid metabolism in Wistar rats, using advanced scientific techniques.
- Results showed that exposed rats had distinct lipid profile changes, increased lipid oxidation, and affected metabolic pathways, contributing to chronic inflammation associated with various diseases connected to arsenic exposure.
Our group has described previously that the endogenous cannabinoid anandamide induces sleep. The hydrolysis of this lipid involves the activity of the fatty acid amide hydrolase (FAAH), which additionally catalyzes the degradation of the satiety factor oleoylethanolamide and the analgesic-inducing lipid palmitoylethanolamide. It has been demonstrated that the inhibition of the FAAH by URB597 increases levels of anandamide, oleoylethanolamide and palmitoylethanolamide in the brain of rats.
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