An Asymptomatic Patient with Fatal Infertility Carried a Swedish Strain of with Additional Deletion in The Plasmid that Belonged to A Different MLST Sequence Type.

Here, we present the first case of asymptomatic genital Chlamydial infection caused by the new emerging () ST13 strain genovar E, which has a double deletion of 377 bp and 17 bp in gene of the cryptic plasmid (ddCT). This case occurred in an infertile patient (case-patient) with a detectable level of Chlamydial antibodies and a spermatozoa deficiency known as azoospermia. Additionally, the ddCT strain showed the presence of a duplication of 44 bp in the plasmid and SNP in , which were known as the typical characteristics of the Swedish variant of (nvCT) genovar E.

First Detection of Swedish' Variant (nvCT) in a Russian Couple with Infertility.

Background: Chronic asymptomatic chlamydial genital infection caused by the wild-type of (wtCT) is the most common bacterial infection causing human infertility. The novel 'Swedish' variant of (nvCT) which contains a 377 bp deletion in a region that is specifically targeted in some nucleic acid amplification tests may impede diagnosis.

Objective: The study aimed to investigate whether nvCT may be a possible cause of infertility in a couple undergoing fertilization (IVF).