The Repurposing of FDA-Approved Drugs as FtsZ Inhibitors against : An In Silico and In Vitro Study.

Unlabelled: (Mtb), the causative pathogen of tuberculosis, remains one of the leading causes of death from a single infectious agent. Furthermore, the growing evolution to multi-drug-resistant (MDR) strains requires de novo identification of drug targets for evaluating candidates or repurposing drugs. Hence, targeting FtsZ, an essential cell division protein, is a promising target.

evaluation of the antagonistic activity of native strains of spp. against spp.

Five samples of agricultural soil and five samples of (P. Mill., 1768) plants with symptoms of wilt and root necrosis were collected in five localities of the state of Tamaulipas, México.

New implications on genomic adaptation derived from the Helicobacter pylori genome comparison.

Background: Helicobacter pylori has a reduced genome and lives in a tough environment for long-term persistence. It evolved with its particular characteristics for biological adaptation. Because several H.