Depressive experiences in inpatients with borderline personality disorder.

We investigate the quality of dependent and self-critical depressive experiences in a hospitalized sample of depressed (n = 17), depressed borderline (n = 29), and borderline non-depressed inpatients (n = 10). Subjects were administered structured diagnostic interviews for axis I and axis II along with the Symptom Checklist-90-Revised Depression Scale (SCL-90-R-DS) and the Depressive Experiences Questionnaire (DEQ). As predicted, there were no differences between the three groups in overall level of impairment or severity of depression.

Characterizing behavioral and psychological symptoms of dementia (BPSD) among geropsychiatric inpatients.

Objective: The purpose of this database analysis was to determine if, upon hospital admission, particular behavioral and psychological symptoms of dementia (BPSD) could be linked to patient characteristics, levels of cognitive or clinical functioning, and/or type of residence before hospitalization.

Methods: Sampled were geropsychiatric inpatients with a primary DSM-IV discharge diagnosis of dementia, who participated in the Mental Health Outcomes, Inc. CQI+(SM) measurement program between January 1, 1996 and December 31, 1999 and who had admission data on all study variables and dementia subtype diagnosis at discharge (N = 2256).

Assessing antipsychotic effectiveness in dementia with the factor structure of the Psychogeriatric Dependency Rating Scale (PGDRS).

Objective: Behavioral and psychological symptoms of dementia (BPSD) impact patient functioning, caregiver burden, and transition to structured living environments. The purpose of this study was to use the derived factor structure of the Psychogeriatric Dependency Rating Scale (PGDRS) to retrospectively assess short-term antipsychotic effectiveness. SETTING AND MEASUREMENT: A principal components factor analysis was conducted with PGDRS admission ratings for a large national sample of hospitalized dementia patients (N = 2747).

Inpatient length of stay and atypical antipsychotic use among elderly patients with psychiatric disorders and Alzheimer's disease.

This study evaluated length of stay (LOS) associated with atypical antipsychotic monotherapy in inpatients with Alzheimer's disease. In addition to sociodemographic information, data were also obtained on severity of illness, medications, used, patient satisfaction, and hospitalization. Sociodemographics and severity of illness at admission were similar in groups taking olanzapine (N = 66), quetiapine (N = 41), and risperidone (N = 147).

Antidepressant prescribing in community cancer care.

Goals: To describe patterns of antidepressant (ADs) prescribing in community oncology practice.

Patients And Methods: Data were collected using an electronic medical record on all staged breast, colon, and lung cancer patients in three community-based oncology practices. The data were analyzed retrospectively, using descriptive and bivariate analyses and multivariate logistic regression modeling.

Diagnostic efficiency of borderline personality disorder criteria in hospitalized adolescents: comparison with hospitalized adults.

Objective: The authors examined the diagnostic efficiency of borderline personality disorder criteria in adolescent inpatients. For comparison, diagnostic efficiency of borderline personality disorder criteria was also examined in a group of concurrently recruited adult inpatients.

Method: Adolescents (N=123) and adults (N=106) were reliably assessed with the Personality Disorder Examination, a semistructured diagnostic interview for DSM-III-R personality disorders.

Association between medical comorbidity and treatment outcomes in late-life depression.

Objectives: Previous studies have demonstrated an association between major depression and physical disability in late life. The objectives of this study were to examine the relationship between specific medical illnesses and the outcomes of treatment for late-life depression.

Design: The study was a longitudinal assessment of medical illness, depression, and disability.

Stability and change of DSM-III-R personality disorder dimensions in adolescents followed up 2 years after psychiatric hospitalization.

We examined the stability of DSM-III-R personality disorder dimensions in a clinical sample of adolescents. Sixty adolescent inpatients were reliably assessed with the Personality Disorder Examination (PDE) soon after admission to the Yale Psychiatric Institute, and were independently reassessed with the same instrument 2 years following discharge. PDE symptom ratings were summed to create dimensional scores for each personality disorder.

Medication prescribing patterns for patients with bipolar I disorder in hospital settings: adherence to published practice guidelines.

Objective: The purposes of this paper were to examine the medication prescribing patterns for bipolar I disorder in hospital settings and to compare them to recently published expert consensus guidelines for medication treatment of bipolar disorder.

Methods: Data were obtained from the 1996-2000 CQI+SM Outcomes Measurement System, on patients age 18 or older admitted to psychiatric inpatient units from over 100 medical-surgical hospitals. A total of 1864 patients with a primary discharge diagnosis of bipolar I or II disorder were identified from a large cohort of hospitalized patients.

Antipsychotic treatment of behavioral and psychological symptoms of dementia in geropsychiatric inpatients.

Behavioral/psychological symptoms of dementia (BPSD) affect caregiver burden and transition from home to hospital or long-term care. The authors examined change in BPSD for dementia patients (from hospital admission to discharge) who were prescribed haloperidol (n= 289), olanzapine (n=209), or risperidone (n=500). Olanzapine was associated with significantly greater overall improvement in BPSD (based on the Psychogeriatric Dependency Rating Scale total score) than risperidone or haloperidol.

Applicability of personality disorder criteria in late adolescence: internal consistency and criterion overlap 2 years after psychiatric hospitalization.

We examined internal consistency and criterion overlap of DSM-III-R personality disorder criteria in late adolescence, 2 years after psychiatric hospitalization. A total of 60 adolescents were assessed with the Personality Disorder Examination. Within-category cohesiveness (internal consistency) was evaluated by coefficient alpha and mean intercriterion correlation (MIC).

Comorbidity of borderline personality disorder with other personality disorders in hospitalized adolescents and adults.

Objective: The authors examined the comorbidity of borderline personality disorder with other personality disorders in a series of consecutively admitted adolescents. For comparison, the comorbidity of borderline personality disorder with other personality disorders was also examined in a series of adults consecutively admitted to the same hospital during the same period.

Method: A total of 138 adolescents and 117 adults were reliably assessed with the Personality Disorder Examination, a semistructured diagnostic interview for DSM-III-R personality disorders.

Effects of alcohol consumption on the treatment of depression among elderly patients.

The authors examined the effects of alcohol use on the short-term and 3-4-month treatment outcomes of patients with late-life depression. Patients (N=2,666) were assessed for symptoms of depression, alcohol use, and disability during an initial inpatient hospitalization and then 3-4 months postdischarge. Contrary to our hypothesis that alcohol consumption imparted a significant additive detriment to treatment outcome in patients already suffering from major depression, the results suggest that treatment was effective even in those with concomitant use of alcohol.

Change in disability follows inpatient treatment for late life depression.

Objectives: The objective of this study was to examine the relationship between functional disability and improvement in late life depression after acute inpatient treatment.

Design: The study was a longitudinal assessment of depression and disability. Patients were assessed during an initial inpatient hospitalization and then 3 months postdischarge.

Concurrent and predictive validity of the personality disorder diagnosis in adolescent inpatients.

Objective: The authors investigated the concurrent and predictive validity of the DSM-III-R diagnosis of personality disorder in adolescents by means of baseline and follow-up assessments of inpatients treated at the Yale Psychiatric Institute.

Method: One hundred sixty-five hospitalized adolescents were reliably assessed by using a structured interview for personality disorder diagnoses as well as two measures of impairment and distress--the Global Assessment of Functioning Scale and the SCL-90-R. Two years after initial assessment, 101 subjects were independently reassessed with the same measures; their functioning was also assessed at this time.

Applicability of personality disorder criteria to hospitalized adolescents: evaluation of internal consistency and criterion overlap.

Objective: The authors examined the applicability of personality disorder criteria to adolescent inpatients by evaluating internal consistency and criterion overlap.

Method: Thirty-eight adolescents and 28 adults were assessed with the Personality Disorder Examination. Within-category cohesiveness (internal consistency) of the criteria was evaluated by examining intercriterion correlations as well as coefficient alpha.

Frequency of personality disorders in two age cohorts of psychiatric inpatients.

Objective: The authors examined the frequency of DSM-III-R personality disorders in adolescent and young adult psychiatric inpatients.

Method: Structured diagnostic interviews were reliably performed with a series of 255 consecutively admitted inpatients (138 adolescents and 117 young adults).

Results: Most personality disorders were diagnosed in similar frequencies in the two study groups.

Controlled study of psychiatric comorbidity in psychiatrically hospitalized young adults with substance use disorders.

Objective: The purpose of this study was to examine DSM-III-R axis I and axis II comorbidity in psychiatrically hospitalized young adults with substance use disorders.

Method: Structured diagnostic interviews were given to 117 consecutive inpatients. Seventy patients with substance use disorders and 47 patients without substance use disorders were compared.

Psychiatric comorbidity differences in male and female adult psychiatric inpatients with substance use disorders.

To examine gender differences in the co-occurrence of DSM-III-R axis I disorders and axis II personality disorders in young adult psychiatric inpatients with substance use disorders (SUDs), a consecutive series of 70 inpatients (33 men and 37 women) with SUD were reliably assessed with structured diagnostic interviews. Higher rates of dysthymia and eating disorders were observed in SUD females and higher rates of cluster A personality disorders were observed in SUD males. No gender differences were found for depression or anxiety in our SUD inpatients; these findings contrast with gender ratios for these disorders in the general population.

Diagnostic comorbidity in hospitalized adolescents with conduct disorder.

We compared the diagnostic comorbidity of DSM-III-R axis I and axis II disorders in a sample of hospitalized adolescents with conduct disorder (CD) and a comparison group of hospitalized adolescents without conduct disorder (non-CD). Of 138 consecutively evaluated adolescents, 76 patients met criteria for CD and 62 did not. On axis I, CD was significantly comorbid with attention-deficit hyperactivity disorder (ADHD) and substance use disorders (SUDs).

Childhood trauma histories in adolescent inpatients.

The authors describe the prevalence of childhood traumatic experiences among adolescent inpatients. A Childhood Trauma Chart Review Scale (CTCRS) was developed to assess traumatic experiences during childhood and adolescence. The CTCRS was reliably applied to the medical records of 75 adolescent inpatients who had been given structured clinical interviews for DSM-III-R diagnoses at the time of admission.

Personality disorders in adolescents with major depression, substance use disorders, and coexisting major depression and substance use disorders.

This study examined the presence of personality disorders in adolescent inpatients with major depression (MDD; n = 45), substance use disorders (SUD; n = 27), or both disorders combined (MDD-SUD; n = 42). A consecutive series of patients were given structured diagnostic interviews for Axes I and II disorders. The groups did not differ with regard to age, gender, ethnicity, socioeconomic status, psychiatric history, or global assessment of functioning.

Gender differences in personality disorders in psychiatrically hospitalized young adults.

We examined gender differences in DSM-III-R personality disorders in psychiatrically hospitalized young adults. Structured diagnostic interviews were reliably performed on a consecutive series of 118 inpatients. Men were significantly more likely to meet criteria for cluster A, schizotypal, and antisocial personality disorders.

Gender differences in personality disorders in psychiatrically hospitalized adolescents.

Objective: The authors examined gender differences in DSM-III-R personality disorders in adolescent psychiatric inpatients.

Methods: Structured diagnostic interviews were reliably performed with a series of 138 consecutively admitted adolescent inpatients. To reduce variability due to heterogeneity of axis I diagnoses, a subgroup of 87 patients with major depression was retested for gender differences.

Conduct disorder, substance use disorders, and coexisting conduct and substance use disorders in adolescent inpatients.

Objective: The authors examined the association between conduct disorder and substance use disorders in adolescent inpatients.

Method: Structured diagnostic interviews were given to 165 adolescent inpatients to assess the presence of DSM-III-R axis I disorders and personality disorders from axis II. Patients with conduct disorder (N = 25), substance use disorders (N = 24), and coexisting conduct and substance use disorders (N = 54) were compared to determine whether additional axis I and axis II disorders presented at significantly different rates.