Publications by authors named "Eddie Siew"

Rationale & Objective: The role of plasma soluble tumor necrosis factor receptor 1 (sTNFR1) and sTNFR2 in the prognosis of clinical events after hospitalization with or without acute kidney injury (AKI) is unknown.

Study Design: Prospective cohort.

Setting & Participants: Hospital survivors from the ASSESS-AKI (Assessment, Serial Evaluation, and Subsequent Sequelae of Acute Kidney Injury) and ARID (AKI Risk in Derby) studies with and without AKI during the index hospitalization who had baseline serum samples for biomarker measurements.

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Introduction: Biomarkers of acute kidney injury (AKI) are often indexed to urine creatinine (UCr) or urine osmolarity (UOsm) to control for urine concentration. We evaluated how these approaches affect the biomarker-outcome association in patients with AKI.

Methods: The Assessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury Study was a cohort of hospitalized patients with and without AKI between 2009 and 2015.

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Article Synopsis
  • Kidney disease is a widespread and costly condition, with a new national system (VA-REINS) set up to track and analyze chronic kidney disease (CKD) among US veterans.
  • In fiscal year 2014, 1.1 million veterans were identified with CKD using strict definitions, and 2.5 million with more lenient criteria, revealing significant prevalence among VA users.
  • The VA invested around $18 billion in CKD care, largely for patients at stage 3, and aims to use VA-REINS for better disease management and improved patient care quality.
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