Publications by authors named "Eda Odakir"
J Pediatr Hematol Oncol
April 2021
Article Synopsis
- IKZF1 mutations, which affect the Ikaros transcription factor, are linked to various serious health issues including recurrent infections and autoimmune diseases.
- The study investigated a specific IKZF1 variant found in a 3-month-old patient with multiple complications and revealed that this variant affects the protein's ability to bind DNA and localize properly within cells.
- The findings suggest that clinicians should consider IKZF1 mutations when diagnosing conditions like autoimmune hemolytic anemia and immunodeficiency in newborns.
