Publications by authors named "Eda Karadag-Oncel"

Background/objectives: This study aimed to investigate the surgical treatment and management of hydrocephalus in infants with meningomyelocele and compare the single-center experience with the previous studies.

Methods: This retrospective study included 81 infants (47 females and 34 males) who underwent meningomyelocele closure surgery and subsequent ventriculoperitoneal (VP) shunt surgery for hydrocephalus. Clinical and demographic data were retrospectively collected from hospital records, focusing on variables such as the timing of VP shunt placement relative to MMC closure, postoperative complications, and the need for shunt revisions.

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Objective: Respiratory syncytial virus (RSV) is the primary etiology of lower respiratory tract infection in children. The fluctuating incidence of RSV, particularly in light of the COVID-19 pandemic, has shifted the spotlight onto preventive strategies. Our study aims to investigate both the risk factors and clinical symptoms of RSV.

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Article Synopsis
  • Vaccines have significantly reduced COVID-19 hospitalizations among adolescents in Turkey, evidenced by a decline in hospitalizations during the vaccination period compared to pre-vaccination.
  • The study revealed that while there were more total hospitalizations during the vaccination period, the proportion of vaccinated adolescents requiring hospitalization was lower, reflecting the effectiveness of the vaccine.
  • Additionally, breakthrough infections in vaccinated adolescents were generally milder and less severe compared to infections in unvaccinated peers, with many being asymptomatic.
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Objective: This study aimed to determine the epidemiology of Acinetobacter species in the last 5 years, the clinical diseases caused by the pathogen, the possible risk factors for infection, and the resistance pattern of the microorganism in our quaternary-care hospital.

Materials And Methods: In this retrospective cohort study, 67 pediatric cases infected with Acinetobacter species in our hospital between January 2017 and December 2021 were analyzed. Demographic characteristics and clinical and laboratory findings were analyzed.

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  • The study explored the occurrence and causes of neonatal meningitis across multiple centers in the country, focusing on the risk factors, complications, and outcomes of affected newborns.
  • Out of 634 cases analyzed, the incidence was found to be 2.51 per 1000 ICU admissions, with a notable mortality rate of 23.5%, primarily caused by Gram-positive bacteria, especially coagulase-negative Staphylococci.
  • Key risk factors for increased mortality included respiratory distress requiring ventilatory support, low birth weight, and lack of antenatal steroid exposure, highlighting severe clinical conditions associated with poor outcomes.
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To investigate coronavirus disease 2019 (COVID-19) in infants aged 0 to 3 months because there is currently a significant gap in the literature on the subject. A cross-sectional study was conducted with the involvement of 19 medical centers across Turkey and 570 infants. The majority of the patients were male (58.

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Article Synopsis
  • The study investigates multisystem inflammatory syndrome in children (MISC) related to COVID-19, focusing on comparing clinical and laboratory characteristics of children hospitalized in ICU versus those who were not.
  • Conducted from June 2021 to January 2022, the observational study included 601 patients, with 157 requiring ICU care, revealing significant differences in demographics, lab results, and disease features.
  • Key findings showed that older age groups and higher levels of certain inflammatory markers increased the likelihood of ICU admission, highlighting the severe impact of MISC on children's health.
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Background: Information on the use of antigen-based SARS-CoV-2 rapid antigen tests (RAT) in children is limited. RATs have been used more frequently, because they are easily applicable, inexpensive, and can be easily performed at home without the need for special equipment. This study was designed to assign the diagnostic test accuracy of the SARS-CoV-2 RAT in daily clinical practice in children.

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Objectives: This study aimed to evaluate parents' attitudes toward lumbar puncture (LP) for their children with suspected central nervous system infection to determine the reasons for rejection and related factors.

Methods: The survey was provided to parents of children (1 month to 18 years old) for whom LP was recommended because of a concern for central nervous system infection. Sociodemographic characteristics and other related factors of parents who did and did not approve of LP were compared statistically.

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Background: There is no specific biomarker used in the diagnosis of COVID-19 and predicting its clinical severity. This study aimed to investigate the utility of ischemia-modified albumin (IMA) in diagnosing and predicting clinical severity in children with COVID-19.

Methods: Between October 2020 and March 2021, 41 cases constituted the COVID-19 group and 41 cases constituted the healthy control group.

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This report describes a case in which diplopia was developed as a finding of postinfectious anti- N -methyl- d -aspartate receptor encephalitis. Infectious encephalitis, especially herpes simplex virus, is essential as it is one of the triggers of autoimmune encephalitis. Even if the cases present unexpected clinical findings, we should be vigilant in terms of autoimmune processes, such as diplopia seen in our case.

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This multi-center point prevalence study evaluated children who were diagnosed as having coronavirus disease 2019 (COVID-19). On February 2nd, 2022, inpatients and outpatients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were included in the study from 12 cities and 24 centers in Turkey. Of 8605 patients on February 2nd, 2022, in participating centers, 706 (8.

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Background: The incidence of vaccine hesitancy is increasing in many countries. This study aims to determine parents` attitudes and related factors regarding COVID-19 vaccine acceptance for themselves and their children aged 12-18.

Methods: A cross-sectional survey was conducted on parents between 16th November and 31st December 2021, after COVID-19 vaccines were initiated for children in Türkiye.

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Background/objectives: The most frequently reported ocular finding in the acute phase of the multisystem inflammatory syndrome in children (MIS-C), is conjunctivitis. More rarely, punctuate epitheliopathy, anterior uveitis and optic disc oedema can be seen. We aimed to investigate the acute and long-term ocular effects of MIS-C.

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Article Synopsis
  • - Antibiotic-associated diarrhea is a common side effect of antimicrobial therapy, and a study was conducted to examine its prevalence among pediatric patients in a specific region.
  • - The study involved 758 pediatric patients who started oral antibiotics, revealing a 10.4% occurrence rate of diarrhea associated with antibiotic use, particularly higher with cephalosporins and in certain geographic areas of Turkey.
  • - The findings highlighted geographic differences in the rate of antibiotic-associated diarrhea, suggesting that while it's not extremely common, it can vary significantly based on location and type of antibiotic used.
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Objective: The aim of this study was to determine the availability of serum amyloid A (SAA) in the diagnosis of coronavirus disease 2019 (COVID-19), to asses disease severity and to predict hospitalization status.

Methods: Between March, 2020 and March, 2021, a total of 80 children (40 cases with COVID-19 and 40 cases in healthy group) were included in this study. Patients were divided into two groups (mild and moderate/severe) to evaluate SAA levels in terms of clinical severity and also hospitalization status.

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Since the COVID-19 pandemic began, various severe acute respiratory syndrome coronavirus 2 variants have been identified with different characteristics than the nonvariant strain. We retrospectively evaluated the demographic and clinical differences in the cohort of hospitalized COVID-19 children (1 month-18 years old) between March 11, 2020, and September 31, 2022, by the time the variants identified in our country predominate. Bonferroni post hoc analysis was performed to compare the differences between the periods.

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Objective: To determine the clinical significance of serum 25-hydroxy (OH) vitamin D levels in pediatric patients with multisystem inflammatory syndrome in children (MIS-C) and compare the vitamin D levels of these patients with those patients with Coronavirus disease-2019 (COVID-19) and healthy controls.

Methods: This study was designed for pediatric patients aged 1 month to 18 years and conducted between July 14 and December 25, 2021. Fifty-one patients with MIS-C, 57 who were hospitalized with COVID-19, and 60 controls were enrolled in the study.

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Objectives: Colistin has come to the fore as a treatment option, especially with the occurrence of multidrug-resistant Gram-negative infections across the world. However, the high nephrotoxic effects of colistin should be taken into consideration in children. The study's primary outcome was to determine the clinical success of the colistin treatment, and the secondary outcome was to detect the side effects related to colistin.

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Objective: Hydatid disease caused by is a parasitic zoonosis and is endemic in Turkey. Clinical manifestations vary and are related to the anatomical location. In this report, we shared the diagnosis, treatment and follow-up of hydatid disease in children with a 10-year experience.

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