Comparative Study on the Anticancer Drug Potential of a Lectin Purified from Aloe Vera and Aloe-Emodin.

Background: The effect of Aloctin, a lectin purified from Aloe vera leaves, and aloe emodin an anthraquinone glycoside purified from the leaves of the same plant, on several cancer cell lines was investigated.

Methods: Aloctin was isolated from A. vera leaf skin by ammonium sulphate precipitation and CNBr-Sepharose 4B-ovalbumin affinity chromatography.

Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method.

Background: Flavonoids are natural compounds with antioxidant, anticarcinogenic, and anti-inflammatory effects.

Aims: To determine the cytotoxic effects of flavonoids and drug resistance related to P-gp on K562 human chronic myeloid leukemia cells. We also aimed to evaluate the therapeutic potential of imatinib and flavonoid combinations.

Implications for degenerative disorders: antioxidative activity, total phenols, flavonoids, ascorbic acid, beta-carotene and beta-tocopherol in Aloe vera.

In order to demonstrate whether the known biological effects of Aloe vera (L.) Burm. fil.