[Does sepsis impair the healing of colonic anastomosis in splenectomized rats?].

Background: To investigate the effect of splenectomy on the healing of colonic anastomoses under normal and septic conditions.

Methods: Forty Wistar rats were assigned into six groups: group 1: sham, group 2: colonic anastomose, group 3: splenectomy, group 4: colonic anastomose plus sepsis, group 5: colonic anastomose plus splenectomy, group 6: colonic anastomose plus splenectomy plus sepsis. The rats underwent a standardized left colonic resection and primary anastomosis and/or splenectomy.

An unusual cause for massive upper gastrointestinal bleeding in children: Dieulafoy's lesion.

Dieulafoy's lesion is a rare cause of severe upper gastrointestinal hemorrhage in children and predominantly occurs in the proximal stomach. We report a case of massive upper gastrointestinal bleeding in a 3-year-old boy that originated from a Dieulafoy's lesion and was treated by epinephrine injection.