Publications by authors named "Ed Pallister"
Article Synopsis
- - COPI is essential for protein transport in cells, mainly recruited by Arf GTPases to form transport intermediates for proteins like Golgi enzymes.
- - The study identifies GORAB, a protein linked to gerodermia osteodysplastica, as a key player in the COPI machinery, aiding in its recruitment to the trans-Golgi network through interactions with Scyl1.
- - Mutations in GORAB disrupt its function and disrupt the retrieval process for Golgi enzymes, leading to issues in glycosylation, which contributes to the disease's development.
