A prospective, randomized, controlled, multicentre trial for secondary prevention in patients with chronic coronary syndrome using a smartphone application for digital therapy: the CHANGE study protocol.

Aims: Coronary artery disease (CAD) remains the leading cause of death worldwide. 'Stable' CAD is a chronic progressive condition, which recent European guidelines recommend referring to as 'chronic coronary syndrome' (CCS). Despite therapeutic advances, morbidity and mortality among patients with CCS remain high.

A novel and simple cardiac magnetic resonance score (PERT) predicts outcome in takotsubo syndrome.

Objectives: To find simple imaging-based features on cardiac magnetic resonance (CMR) that are associated with major adverse cardiovascular events (MACE) in takotsubo syndrome (TTS).

Methods: Patients with TTS referred for CMR between 2007 and 2021 were retrospectively evaluated. Besides standard CMR analysis, commonly known complications of TTS based on expert knowledge were assessed and summarised via a newly developed PERT score (one point each for pleural effusion, pericardial effusion, right ventricular involvement, and ventricular thrombus).

Smartphone-guided secondary prevention for patients with coronary artery disease.

Introduction: Coronary artery disease (CAD) is the leading cause of death worldwide. Lifestyle change is a crucial part of secondary prevention. Only 30% of CAD patients follow the corresponding guideline recommendations.

Quantitative measurements of the mechanical properties of human bone tissues by scanning acoustic microscopy.

The quantitative scanning acoustic microscopy is used for determination of the acoustic impedance of human femoral bones in the micrometer scale. The method is introduced and demonstrated at prepared bone surfaces with different cutting angles referring to the bone axis. First measurements show weak variations of the elastomechanical properties with angles.

[Mechanical changes in bone after roentgen irradiation with low dosage].

We investigated the micromechanical properties using doses from 1 up to 7 Gray and could observe a roughening on the surface of the bone material in the microscopic range by scanning acoustic microscopic measurements. In addition, a preceding irradiation promoted an extension of microcracks during the polishing process indicating an embrittlement. After irradiation and removal of the surface layer, the SAM measurements indicate a preferential increasing of hardness of softer regions.