Publications by authors named "Eby I Herve Menan"
Meta-Analysis of Data from Four Clinical Trials in the Ivory Coast Assessing the Efficacy of Two Artemisinin-Based Combination Therapies (Artesunate-Amodiaquine and Artemether-Lumefantrine) between 2009 and 2016.
Trop Med Infect Dis
December 2023
Article Synopsis
- Artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) are the first-line treatments for uncomplicated malaria in the Ivory Coast, with various studies examining their efficacy.
- This meta-analysis aimed to assess malaria treatment failures in randomized control trials comparing AL and ASAQ between 2009 and 2016, utilizing data from four multicenter studies.
- Results indicated high clinical and parasitological responses above 95% for both drug combinations, but a higher recurrence of infection was observed in the AL group compared to ASAQ, with most treatment failures classified as new infections after molecular testing.
The extension of resistance to existing antimalarial drugs is worrying. Faced with this problem, the search for new and effective molecules is necessary. In this context, six chalcone derivatives (B1, B11, B14, B17, SCA02 and SCA03) were tested on field isolates and then reference strains to evaluate their antiplasmodial activity by using the Rieckmann semi-microtest, recommended by WHO, for in vitro and ex vivo activity tests.
View Article and Find Full Text PDFIntroduction: Epidemiology of these disorders, mainly caused by mycosis, is little known in the Ivory Coast. The aim of this study was to determine the different clinical aspects of intertrigos caused by fungal infections.
Methods: We conducted a cross-sectional study in the Department of Clinical Dermatology at the University Hospital in Yopougon (Abidjan, Ivory Coast) from April to October 2012.
Introduction. The characterization of genetic profile of Plasmodium isolates from different areas could help in better strategies for malaria elimination. This study aimed to compare P.
View Article and Find Full Text PDFObjectives: Fungal infections of the scalp commonly affect the pediatric population. These infections are caused by dermatophytes that are able to invade the keratinized structures of skin, hair, and nails. This study aimed to analyze the epidemiology of fungal scalp infections in southern Ivory Coast during 2008-2009.
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