Publications by authors named "Ebru Ongun"

Objectives: To examine citrate anticoagulation in continuous renal replacement therapy (CRRT) in the PICU.

Design: Post hoc analysis of a curated, multicenter dataset collected from January 1, 2022, to June 1, 2023.

Setting: Seven PICUs in Turkey.

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Article Synopsis
  • Inborn errors of immunity (IEI) are genetic diseases leading to immune system dysfunction, with this study focusing on patients diagnosed in a pediatric intensive care unit (PICU).
  • Out of 753 admissions over three years, 33 new IEI cases were identified, with a higher prevalence of immunodeficiencies with immune dysregulation and combined immunodeficiencies, often triggered by severe viral and life-threatening infections.
  • The study found a high mortality rate of 58%, emphasizing the critical need for early diagnosis, treatment, and improved screening methods for better outcomes in IEI patients.
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  • The study aimed to differentiate between COVID-19 and other respiratory viral infections in critically ill children to prioritize care and avoid neglecting non-COVID cases.
  • Conducted in 24 pediatric intensive care units, the research evaluated radiological findings in 225 patients from March to May 2020, with 81 confirmed COVID-19 cases.
  • Results showed that chest X-rays of COVID-19 patients were more likely to appear normal, while other viruses like rhinovirus showed distinct patterns, indicating non-specific radiological findings in COVID-19.
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Background: Severe traumatic injuries not only constitute an important population of pediatric intensive care unit (PICU) but they also play a major role in mortality and morbidity. Mortality risk assessment of traumatic injuries in the PICU is a delicate issue as it influences the treatment decisions. BIG score (Base Deficit +[2.

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  • The study aims to evaluate the skills of pediatric healthcare providers in Turkey regarding the recognition of heart rhythm abnormalities and the use of defibrillators, emphasizing the necessity of BLS and ALS training for improved emergency care outcomes.* -
  • Conducted as a cross-sectional survey involving 716 healthcare participants, findings indicated that a majority had received BLS-ALS training, leading to increased confidence and knowledge in performing defibrillation procedures, especially among trained physicians.* -
  • Results showed that non-certified healthcare providers struggled with administering correct doses during cardioversion and defibrillation, highlighting the importance of proper training in improving the effectiveness of emergency interventions in pediatric settings.*
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Background/aim: To characterize the clinical course of noninvasive positive pressure ventilation (NIPPV) and high flow humidified nasal cannula ventilation (HFNC) procedures; perform risk analysis for ventilation failure.

Material And Methods: This prospective, multi-centered, observational study was conducted in 352 PICU admissions (1 month-18 years) between 2016 and 2017. SPSS-22 was used to assess clinical data, define thresholds for ventilation parameters and perform risk analysis.

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Background: Implementation of checklists has been shown to be effective in improving patient safety. This study aims to evaluate the effectiveness of implementation of a checklist for daily care processes into clinical practice of pediatric intensive care units (PICUs) with limited resources.

Methods: Prospective before-after study in eight PICUs from China, Congo, Croatia, Fiji, and India after implementation of a daily checklist into the ICU rounds.

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Aim: To analyze the impact of Tranexamic acid (TXA) on perioperative hemodynamics in craniosynostosis surgery.

Material And Methods: Data of thirty-six children (operated between 2014-2017) were categorized into two groups depending on TXA delivery. Patient demographics, preoperative, intraoperative, postoperative data on hemostasis and metabolic outcomes were recorded.

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Background/aim: Declined morbidity rates after craniosynostosis surgery indicate bypassing the pediatric intensive care unit (PICU) course to minimize treatment costs and bed usage. The aim of this study is to examine the incident rates of PICU admission and assess its necessity. Materials and methods: A retrospective analysis of 41 patients (operated on by open surgical techniques) between July 2011 and December 2015 was carried out.

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Crohn's disease (CD), known as the disease of gastrointestinal system, is a granulamatous systemic disorder with extraintestinal manifestations including the respiratory system. The resemblance in the embriological origins and the immunities of both organ systems' mucosae, also the circulating immune complexes and the autoantibodies are accepted as contributing factors. The shift of inflammation may become prominent when the colon is removed after colectomy and independent of the bowel disease activity; pulmonary involvement may be exarbecated.

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