The complementary benefit of anterior segment optical coherence tomography in penetrating keratoplasty.

Purpose: To evaluate the utility of anterior segment optical coherence tomography (AS-OCT) assessment in the pre- and postsurgical management of full-thickness corneal grafts.

Methods: Seventy eyes of 58 patients who had penetrating keratoplasty were included in the study. High resolution AS-OCT scans of the cornea and the anterior segment were performed before and after transplantation in 17 eyes with the Visante™ optical coherence tomography.

Intraoperative use of AS-OCT during intrastromal corneal ring segment implantation.

Background And Objective: To evaluate femtosecond laser-created tunnels intraoperatively by anterior segment optical coherence tomography (AS-OCT) during intrastromal corneal ring segment implantation.

Patients And Methods: The study prospectively examined 13 eyes of 11 patients who underwent intrastromal corneal ring segment surgery with the aid of femtosecond laser. All eyes had keratoconus as the primary diagnosis.

Assessment of intrastromal corneal ring segment position with anterior segment optical coherence tomography.

Background And Objective: To examine the exact position of implanted Keraring (Mediphacos, Belo Horizonte, Brazil) segments by high-resolution anterior segment optical coherence tomography (AS-OCT).

Patients And Methods: This study included 17 eyes of 13 patients with keratoconus who underwent uneventful intracorneal ring segment implantation with the aid of femtosecond laser. Eyes were evaluated by AS-OCT at the third postoperative month.

Short-term effects of a single intravitreal bevacizumab injection on retinal vessel calibre.

Purpose:   The aim was to investigate the short-term effects of a single intravitreal bevacizumab injection on the retinal vessel calibre in patients with neovascular age-related macular degeneration and in patients with diabetic macular oedema.

Methods:   Twelve patients with neovascular age-related macular degeneration and eight patients with diabetic macular oedema were included in the study. All patients received an intravitreal injection of 1.

Comparison of non-contact methods for the measurement of central corneal thickness.

Background And Objective: This study examined the repeatability of and agreements between central corneal thickness measurements obtained by four different non-contact pachymetry devices.

Patients And Methods: Seventy-eight eyes of 39 subjects were included. Central corneal thickness of each eye was measured by Visante optical coherence tomography (OCT) (Carl Zeiss Meditec Inc.

Corneal biomechanical properties of patients with pseudoexfoliation syndrome.

Purpose: To assess the corneal biomechanical properties of patients with pseudoexfoliation syndrome (PEX syndrome).

Methods: Fifty-two eyes of 52 patients (27 unilateral and 25 bilateral) and 42 eyes of 42 age-matched control subjects were enrolled in the study. Metrics of corneal biomechanical properties, including corneal hysteresis (CH) and corneal resistance factor (CRF), were measured with the ocular response analyzer (ORA).

Influence of intrastromal corneal ring segment implantation on corneal biomechanical parameters in keratoconic eyes.

Purpose: To assess the influence of intrastromal corneal ring segment (ICRS) implantation on corneal biomechanics in patients with keratoconus.

Methods: Patients with keratoconus who underwent femtosecond laser-assisted ICRS (Keraring) implantation were evaluated with the ocular response analyzer (ORA). Metrics of corneal biomechanical parameters, including corneal hysteresis (CH) and corneal resistance factor (CRF) were measured both before and after surgery.

Fundus autofluorescence in acute and chronic central serous chorioretinopathy.

Background: A prospective evaluation of the pattern of fundus autofluorescence in cases of acute versus chronic central serous chorioretinopathy (CSR).

Methods: A prospective, cross-sectional, single-centre investigation was performed using three diagnostic techniques, namely, fundus autofluorescence, optical coherence tomography and fundus fluorescein angiography to evaluate a sample of patients (n = 42 eyes) with both acute (n = 25 eyes) and chronic (n = 17 eyes) CSR.

Results: Hypoautofluoresecence was found in 80 per cent (20 eyes) and 88.

Glutathione S-transferase M1, GSTT1 and GSTP1 genetic polymorphisms and the risk of age-related macular degeneration.

Purpose: To determine the possible effects of glutathione S-transferase (GST) M1, GSTT1 and GSTP1 genetic polymorphisms on the risk of developing age-related macular degeneration (AMD).

Patients And Methods: This case-control study included a total of 120 patients with AMD (65 with dry-type AMD and 55 with wet-type AMD) and 198 disease-free controls. GSTM1 and GSTT1 polymorphisms were analyzed by using a multiplex polymerase chain reaction (PCR), and GSTP1 polymorphism was detected by real-time PCR assay.

Anterior segment optical coherence tomography findings of acute hydrops in a patient with keratoconus.

The authors describe the anterior segment optical coherence tomography (AS-OCT) findings of a 25-year-old patient with acute hydrops associated with keratoconus. The patient presented with decreased visual acuity, pain, and redness in the left eye. The symptoms, clinical presentation, and topographical findings of the right eye confirmed this condition to be acute corneal hydrops.

AS-OCT as a tool for flap thickness measurement after femtosecond-assisted LASIK.

Background And Objective: to investigate the efficacy of anterior segment optical coherence tomography (AS-OCT) for calculating flap thickness in femtosecond laser-assisted laser in situ keratomileusis.

Patients And Methods: fifty-one eyes of 26 patients with myopia and myopic astigmatism were included in this prospective study. High-resolution corneal images were evaluated at 1 week and 1 month postoperatively.

Changes in corneal biomechanics in patients with keratoconus after penetrating keratoplasty.

Purpose: To examine the biomechanical properties of keratoconic eyes following penetrating keratoplasty and to compare results with the biomechanical characteristics of manifest keratoconus, forme fruste keratoconus and normal eyes as measured with the Reichert ocular response analyzer (ORA).

Methods: This retrospective analysis comprised a total of 169 eyes: 34 eyes with forme fruste keratoconus (group FF), 36 eyes with manifest keratoconus (Group KC), 36 eyes that have undergone penetrating keratoplasty (Group PK) and a control group of 63 normal eyes (Group N). Corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated intraocular pressure, and Goldmann correlated intraocular pressure were measured by ORA.

Descemet-stripping automated endothelial keratoplasty in eyes with toxic anterior segment syndrome after cataract surgery.

Purpose: To report the results of Descemet-stripping automated endothelial keratoplasty (DSAEK) in eyes with toxic anterior segment syndrome (TASS) after cataract surgery.

Setting: Department of Ophthalmology, Istanbul University Cerrahpaşa Medical Faculty, Istanbul, Turkey.

Methods: In this prospective study of consecutive patients who had DSAEK for corneal failure due to TASS, the main outcome measures were corneal clarity, mean spherical equivalent (SE) refraction, preoperative and postoperative visual acuities, central corneal thickness, and endothelial cell count (ECC).

Assessment of anterior chamber depth using Visante optical coherence tomography, slitlamp optical coherence tomography, IOL Master, Pentacam and Orbscan IIz.

Aims: To assess and compare the anterior chamber depth (ACD) by different anterior segment imaging techniques.

Methods: Eighty healthy eyes of 40 patients were recruited, and 3 consecutive measurements of ACD were determined prospectively utilizing Visante optical coherence tomography (OCT), slitlamp (SL) OCT, IOL Master, Pentacam and Orbscan IIz. The statistical significance of interdevice differences between measurements was evaluated by one-way ANOVA and Bland-Altman analysis.

Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related macular degeneration.

Purpose: Oxidative stress seems to be an important factor in the development of age-related macular degeneration (AMD). The role of DNA repair mechanisms has also received attention recently in AMD pathogenesis. This case-control study was conducted to determine the frequency of polymorphisms in two DNA repair enzyme genes, xeroderma pigmentosum complementation group D (XPD), codons 312 and 751, and x-ray cross-complementing group 1 (XRCC1), codons 194 and 399, in patients with AMD and in disease-free control subjects.

Assessment and comparison of anterior chamber dimensions using various imaging techniques.

Background And Objective: To assess and compare the horizontal dimensions of the anterior chamber by different anterior segment imaging techniques.

Patients And Methods: Eighty eyes of 40 patients without any ocular disease or previous ocular surgery were recruited and three consecutive measurements of internal anterior chamber diameter and white-to-white distance (WTW) parameters were determined.

Results: Mean internal anterior chamber diameter was 11.

Assessment of anterior chamber angle using Visante OCT, slit-lamp OCT, and Pentacam.

Purpose: To assess and compare the anterior chamber angle (ACA) by different anterior segment imaging techniques.

Methods: Forty healthy eyes of 40 normal subjects were recruited and 3 consecutive measurements of ACA were determined prospectively utilizing Visante optical coherence tomography (OCT), slit-lamp OCT (SL-OCT), and Pentacam. Statistical significance of interdevice differences between measurements was evaluated by Wilcoxon signed rank test and Bland-Altman analysis.

Diurnal variation of corneal biomechanics and intraocular pressure in normal subjects.

Purpose: To assess and investigate the relationship between diurnal variations in intraocular pressure (IOP) and biomechanical properties of cornea.

Methods: Sixty-two healthy volunteers were recruited. Corneal compensated IOP (IOPcc), Goldmann-correlated IOP (IOPg), corneal resistance factor (CRF), and corneal hysteresis (CH) parameters were recorded by the Ocular Response Analyzer (ORA).

Correlation of retinal sensitivity and retinal thickness in central serous chorioretinopathy.

Aim: To evaluate the correlation of microperimetry (MP) and optical coherence tomography (OCT) in eyes having acute onset of central serous chorioretinopathy (CSCR).

Methods: After a detailed ophthalmological examination, all cases were evaluated by fundus fluorescein angiography, OCT and MP. Mean macular thickness was detected by OCT.

Immediate evaluation of the flaps created by femtosecond laser using anterior segment optical coherence tomography.

Background And Objective: To demonstrate the practical and functional evaluation of flaps created intraoperatively by femtosecond laser using anterior segment optical coherence tomography (AS-OCT).

Patients And Methods: The study prospectively examined 11 eyes of 6 patients who underwent uneventful LASIK surgery with the aid of the IntraLase femtosecond laser (IntraLase Corp., Irvine, CA).

Quantitative assessment of anterior chamber volume using slit-lamp OCT and Pentacam.

Purpose: To quantitatively assess and compare the anterior chamber volume (ACV) by different anterior segment imaging techniques.

Methods: Forty healthy eyes of 40 patients were recruited and three consecutive measurements of ACV were determined prospectively utilizing SL-OCT and Pentacam. Statistical significance of interdevice differences between measurements was evaluated by unpaired t test and Bland-Altman analysis.

Corneal biomechanical properties and intraocular pressure changes after phacoemulsification and intraocular lens implantation.

Purpose: To evaluate corneal viscoelastic and intraocular pressure (IOP) changes measured by an ocular response analyzer (ORA) after phacoemulsification and intraocular lens (IOL) implantation.

Setting: Yeditepe University Department of Ophthalmology, Istanbul, Turkey.

Methods: Fifty-one eyes scheduled for cataract surgery were included in the study.

Anterior segment optical coherence tomography measurement of anterior chamber depth and angle changes after phacoemulsification and intraocular lens implantation.

Purpose: To use anterior segment optical coherence tomography (AS-OCT) to evaluate anterior chamber depth (ACD) and angle after phacoemulsification and intraocular lens (IOL) implantation.

Setting: Department of Ophthalmology, Yeditepe University, Istanbul, Turkey.

Methods: Forty-seven eyes (37 patients) had uneventful phacoemulsification and IOL implantation through a clear corneal incision.

Atypical presentation of multiple evanescent white dot syndrome (MEWDS).

Purpose: To present fundus autofluorescence (FAF), indocyanine green angiography (ICGA), and microperimetry (MP) findings of a patient with multiple evanescent white dot syndrome (MEWDS).

Methods: Observational case report.

Results: A 30-year-old woman with blurry vision was referred for evaluation.