Physicochemical Characterization and Evaluation of the Binding Effect of Schweinf Gum in Granule and Tablet Formulations.

This study is aimed at evaluating the binding effect of gum in granule and tablet formulations using paracetamol as a model drug. Some physicochemical properties of the purified gum such as pH, the presence of tannin and dextrin, solubility, viscosity, loss on drying, total ash value, water solubility index, swelling power, moisture sorption, and powder flow properties were investigated. Paracetamol granules were prepared using wet granulation method at 2%, 4%, 6%, and 8% / of the gum and compared with granules prepared with reference binders (PVP K-30 and Acacia BP) in similar concentrations.

Safety and Biopharmaceutical Challenges of Excipients in Off-Label Pediatric Formulations.

Background: One of the major challenges in pediatric treatment is the lack of suitable drug preparations specifically designed and marketed for children. Most of the FDA approved drug formulations for adults have not been approved for use in pediatric patients. Shortage of suitable pediatric dosage information often leads health professionals to use adult formulations in an off-label manner.

Evaluation of Hochst ex A. Rich Mucilage as Suspending Agent in Metronidazole Benzoate Suspension.

Various species of the genus have been investigated for different pharmaceutical applications as excipients, yet a study on the potential use of mucilage (GFM) as a suspending agent is lacking. Thus, this study is aimed at evaluating the efficacy of mucilage (GFM) as a suspending agent in metronidazole benzoate suspension. The suspensions were prepared using 0.

Drug Use during Acute Illness in Tigray Region, Northern Ethiopia: A Household Study.

Background: Drug use study in the community enables health authorities to understand pattern of drug utilization and its related aspects. This, in turn, can help to develop rational drug policies to be harmonized in accordance to the need of the community.

Objective: The aim of this study was to assess drug use during acute illness by the general population in Tigray region, Northern Ethiopia.