Quality of warfarin management following transfer from an anticoagulation clinic to primary care.

Background: Advances in alternative oral anticoagulants has reduced use and clinician comfort with warfarin. Our specialty anticoagulation clinic (AC) operates at maximum capacity and must transfer patients to accept new referrals.

Objectives: To compare time within therapeutic range (TTR) during 6 months of AC care versus following transfer to primary care for a minimum of 6 months and to a maximum of 24 months.

Effect of Pressure Loading on Heel Skin Temperature and Moisture in Healthy Volunteers: Preliminary Results.

Recent studies emphasize the significance of skin microclimate in the prevention of pressure injuries (PI). The objective was to evaluate the effect of pressure loading on skin temperature and moisture in the heels of healthy adults. This is a before-and-after study performed at Brazil, in October 2022.

Assessment of immunosuppression induction with basiliximab compared to antithymocyte-globulin in adult heart transplant patients.

Background: Patients undergoing heart transplants are at risk of rejection which can have significant morbidity and mortality. Induction immunosuppression at the time of transplant reduces the early risk and has additional benefits. The induction agent of choice within our program was changed from rabbit antithymocyte-globulin (rATG) to basiliximab, so it was necessary to evaluate whether this had any impact on patient outcomes.

Efficient extraction of lignin from moso bamboo by microwave-assisted ternary deep eutectic solvent pretreatment for enhanced enzymatic hydrolysis.

Applications of deep eutectic solvent (DES) systems to separate lignocellulosic components are of interest to develop environmentally friendly processes and achieve efficient utilization of biomass. To enhance the performance of a binary neutral DES (glycerol:guanidine hydrochloride), various Lewis acids (e.g.

Heel skin microclimate control: Secondary analysis of a self-controlled randomized clinical trial.

Objective: this study was undertaken to evaluate the efficacy of multilayer polyurethane foam with silicone (MPF) compared to transparent polyurethane film (TPF) dressings in the control of heel skin microclimate (temperature and moisture) of hospitalized patients undergoing elective surgeries.

Method: the study took of a secondary analysis of a randomized self-controlled trial, involving patients undergoing elective surgical procedure of cardiac and gastrointestinal specialties in a university hospital in southern Brazil, from March 2019 to February 2020. Patients served as their own control, with their heels randomly allocated to either TPF (control) or MPF (intervention).

Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients.

A growing number of druggable targets and national initiatives for precision oncology necessitate broad genomic profiling for many cancer patients. Whole exome sequencing (WES) offers unbiased analysis of the entire coding sequence, segmentation-based detection of copy number alterations (CNAs), and accurate determination of complex biomarkers including tumor mutational burden (TMB), homologous recombination repair deficiency (HRD), and microsatellite instability (MSI). To assess the inter-institution variability of clinical WES, we performed a comparative pilot study between German Centers of Personalized Medicine (ZPMs) from five participating institutions.

Changes in Physical Fitness during the COVID-19 Pandemic in German Children.

With the beginning of the COVID-19 pandemic in December 2019, each country has developed strategies to try to control the virus. The restrictions and subsequent consequences also limited the possibilities and structures for being physically active. Therefore, the aim of this study was to examine changes in physical fitness in a cohort that was investigated over an extended period.

Effect of New Evidence on Antithrombotic Therapies in Atrial Fibrillation Patients Who Undergo Percutaneous Coronary Intervention in Alberta, Canada.

Background: Trials have addressed the combined use of direct oral anticoagulants (DOACs) and antiplatelets in atrial fibrillation (AF) patients undergoing percutaneous coronary intervention (PCI). These trials may have changed prescribing patterns.

Methods: This administrative audit of Albertans with AF undergoing PCI described antithrombotic therapy before vs after publication of the PIONEER AF-PCI (An Oen-label, Randomized, Controlled, Multicenter Study Explorng Tw Treatmet Stratgis of ivaroxaban and a Dose-Adjusted Oral Vitamin K Antagonist Treatment Strategy in Patients With trial ibrillation Who Undergo ercutaneous oronary ntervention) trial results.

The Fitness Barometer: A Best Practice Example for Monitoring Motor Performance With Pooled Data Collected From Practitioners.

Motor Performance (MP) in children is an important resource for their future active lifestyle and health. Monitoring of MP is crucial to derive information of trends and to implement specific programs on the base of current MP levels. A variety of MP assessment tools exist, making it difficult to determine a "gold-standard" for assessment and to compare the findings.

Prevention of pressure injury in the operating room: Heels operating room pressure injury trial.

The objective was to evaluate the efficacy of multi-layered silicone foam (intervention) compared with transparent polyurethane film (control) in preventing heel pressure injuries caused by surgical positioning of individuals undergoing elective surgery. It was designed an intra-patient, open, parallel, randomised controlled trial was conducted in a university hospital in southern Brazil, from March 2019 to February 2020, with patients undergoing elective surgeries of cardiac and gastrointestinal specialties. The patients who met the selection criteria constituted, simultaneously, a single group receiving the intervention and active control, through paired analysis of the cutaneous sites (right heel and left heel).

Secular Trends in Physical Fitness of Children and Adolescents: A Review of Large-Scale Epidemiological Studies Published after 2006.

Physical fitness (PF) of children and adolescents is an important resource for their future health. Population-based studies, however, rarely report secular changes of PF, although monitoring of these is crucial to deriving information for adequate interventions. This review aims to report trends in PF of children and adolescents.

Interventions to Promote Positive Affect and Physical Activity in Children, Adolescents and Young Adults-A Systematic Review.

Interventions to promote physical activity (PA) in children, adolescents and young adults based on social-cognitive theories often fail to increase PA. In recent years, affect-based approaches have gained interest, but the current state of research is not sufficiently reported. Therefore, a systematic review about the influence of interventions to promote positive affect and PA enjoyment and PA in children, adolescents and young adults was conducted.

Effect of Secondary Metabolites on the Growth of Brown-Rot () and White-Rot () Fungi.

We investigated the antifungal activities of an endophytic fungus identified as , found on a loblolly ( L.) pine bolt in Louisiana during routine laboratory microbial isolations. The specific objectives were to determine the inhibitory properties of secondary metabolites (crude extract) on the mycelial growth of a brown-rot fungus and a white-rot fungus , and to determine the effective concentration of crude preparation against the two decay fungi .

[Effectiveness of Biofeedback for Primary Headache - A Randomized Controlled Study].

Background: Biofeedback-treatment for primary headache is highly recommended. Its expenses are mostly not or not completely covered by health funds, hindering the implementation in the care system. This randomized controlled study aimed at evaluating the efficacy of a biofeedback-treatment for primary headache in the outpatient care system all over Germany.

Skin temperature as a clinical parameter for nursing care: a descriptive correlational study.

Objective: To identify the skin temperature in different body areas of hospitalised individuals in the surgical unit, without risk of developing a pressure ulcer (PU).

Methods: A descriptive, correlational and cross-sectional study, carried out May-October 2017, in a surgical unit of a university hospital in southern Brazil. Temperature was measured at the bony prominences including scapula, elbow, trochanters and heels, on both sides of the body, as well as occipital and sacral regions.

Demethylation of Alkali Lignin with Halogen Acids and Its Application to Phenolic Resins.

Lignin, a byproduct from the chemical processing of lignocellulosic biomass, is a polyphenolic compound that has potential as a partial phenol substitute in phenolic adhesive formulations. In this study, HBr and HI were used as reagents to demethylate an alkali lignin (AL) to increase its hydroxyl content and thereby enhance its reactivity for the preparation of phenolic resins. Analyses by FT-IR, H-NMR and 2D-NMR(HSQC) demonstrated both a decrease in methoxyl groups and an increase in hydroxyl groups for each demethylated lignin (DL).

Using AutoCAD software to measure venous leg ulcers: a reproducibility assessment study.

Objective: To assess the reproducibility of using AutoCAD software to measure the area of venous leg ulcers (VLUs).

Method: Data from patients with VLUs were collected between March and July 2015, using data collection forms and photographing the different ulcers. A researcher and five nurses collected the data.

Measurement of the area of venous ulcers using two software programs.

Objective: to compare the measurement area of venous ulcers using AutoCAD(r) and Image Tool software.

Method: this was an assessment of reproducibility tests conducted in a angiology clinic of a university hospital. Data were collected from 21 patients with venous ulcers, in the period from March to July of 2015, using a collection form and photograph of wounds.

Effect of biochar amendment on tylosin adsorption-desorption and transport in two different soils.

The role of biochar as a soil amendment on the adsorption-desorption and transport of tylosin, a macrolide class of veterinary antibiotic, is little known. In this study, batch and column experiments were conducted to investigate the adsorption kinetics and transport of tylosin in forest and agricultural corn field soils amended with hardwood and softwood biochars. Tylosin adsorption was rapid at initial stages, followed by slow and continued adsorption.

Partial dissolution of ACQ-treated wood in lithium chloride/N-methyl-2-pyrrolidinone: separation of copper from potential lignocellulosic feedstocks.

A cellulose solvent system based on lithium chloride (LiCl) in N-methyl-2-pyrrolidinone (NMP) was used to assess the merits of partial dissolutions of coarsely ground wood samples. Alkaline Copper Quaternary (ACQ)-treated pine wood was of particular interest for treatment given the potential to generate a copper-rich stream apart from solid and/or liquid lignocellulosic feedstocks. Treatment with NMP alone gave yields of soluble materials that were higher than typical extractives contents thereby suggesting a limited degree of wood dissolution.

Hydrothermal transformation of Chinese privet seed biomass to gas-phase and semi-volatile products.

Hydrothermal (HT) treatment of seeds from Chinese privet (Ligustrum sinense), a non-native and invasive species in the southeastern United States, was examined with respect to the generation of gas-phase and semi-volatile organic chemicals of industrial importance from a lipid-rich biomass resource. Aqueous seed slurries were transformed into biphasic liquid systems comprised of a milky aqueous phase overlain by a black organic layer. Present in the headspace were elevated levels of CO(2) and acetic acid.

A preliminary investigation of insect colonisation and succession on remains in New Zealand.

A preliminary, systematic field study on the process of decomposition and associated insects was conducted, for the first time, in New Zealand. Using pig carcasses as an animal model for human decomposition, insect colonisation and succession was monitored in three different habitats in the Auckland region where remains are likely to be found. A significant difference in the rates of decomposition was found among the three different habitats of an open field, coastal sand dune area and native bush during the autumn/winter season.

Screening for depression in stroke: relationship to rehabilitation efficiency.

Depression is common after stroke but is often not diagnosed. Its presence may impair progress during rehabilitation and limit functional improvement after discharge. We investigated the use of the Geriatric Depression Scale (GDS) to screen for depression among acute stroke patients.