Institutional Variability in Patient Radiation Doses ≥5 Gy During Percutaneous Coronary Intervention.

Objectives: The aim of this study was to evaluate institutional variability in high radiation doses during percutaneous coronary intervention (PCI).

Background: It is unknown whether radiation safety practices are optimally applied across institutions performing PCI.

Methods: Using data from a large statewide registry, PCI discharges between July 1, 2016, and March 31, 2018, with a procedural air kerma (AK) recorded were analyzed.

Mosquitoes of Thule Air Base, Greenland.

Thule Air Base in western Greenland had a previously uncharacterized mosquito pest problem. Swarms of bloodfeeding mosquitoes have been reported from June to late August, but the species were unknown. We conducted a base-wide mosquito vector survey from June to July 2012.

Single unit activity in the lateral septum and central nucleus of the amygdala in the elevated plus-maze: a model of exposure therapy?

The central nucleus of the amygdala (CeA) is a major output region of the amygdala involved in organizing the expression of fear. There is also evidence that the lateral septum (LS) provides inhibitory control of neurons in CeA and is involved in the relief of fear. This study examined single unit activity in the lateral septum (LS) and the central nucleus of the amygdala (CeA) in the open and closed arms of the elevated plus-maze, a highly validated animal model of fear and anxiety.

Electrophysiological analysis of the interaction between the lateral septum and the central nucleus of the amygdala.

Evidence suggests that the lateral septum (LS) and the central nucleus of the amygdala (CeA) play opposing roles in the modulation of fear and anxiety. The current study examined the interaction of the two structures in the albino rat by electrically stimulating each and recording single-unit activity in the other. In each case, electrical stimulation consisted of 50 trains of 5 pulses 800μA in amplitude, 0.

Type A Aortic Dissection Presenting with Acute Lower Extremity Vascular Insufficiency in the Absence of Chest Pain.

We report a case of a 53 year-old man with a history of hypertension presenting with acute left lower extremity parasthesias and pulselessness initially presumed to be secondary to arterial thrombosis or embolism. Work-up included a transthoracic echocardiogram which revealed an aortic dissection at the level of the aortic root extending to the visualized portions of the descending aorta. Type A aortic dissections are relatively rare, with the vast majority of patients presenting with chest pain.

Kindling of the lateral septum and the amygdala: effects on anxiety in rats.

Long-term kindling of limbic system structures may produce substantial changes in emotional behavior in rats. This study examined long-term changes in two kindled structures that have opposite effects on anxiety, the lateral septum and the central nucleus of the amygdala. The purpose of the experiment was to examine the specificity of the emotional effects of kindling by employing a double dissociation design.

Direct stenting compared to balloon predilation in drug-eluting stents: one-year outcomes from the DEScover Registry.

Objectives: We sought to examine the determinants and outcomes of direct stenting (DS) compared to predilation with drug-eluting stents (DES).

Background: Limited data suggest that DS with DES is feasible and may reduce restenosis compared to predilation. Whether DS improves clinical outcomes in unselected patients treated with DES is unknown.

Effects of chlordiazepoxide on single-unit activity in the septal region of the freely moving rat: aversive vs. non-aversive contexts.

Evidence suggests that stimuli that have the property of inhibiting fear in a Pavlovian fear conditioning paradigm increase cellular activity in the lateral septum, a result consistent with the idea that the lateral septum is actively involved in the inhibition of fear. The experiments reported here were designed to determine if an anxiolytic drug with fear-inhibiting properties would also increase neuronal activity in the lateral septum in a manner that might relate to its mechanism of action as an anxiolytic. An experiment was performed to compare the effects of the benzodiazepine anxiolytic chlordiazepoxide (CDP) upon single-unit activity in the septal region of the rat brain during Pavlovian aversive conditioning with the effects of CDP in a non-aversive context.

Corticotropin-releasing factor in the dorsal raphe nucleus regulates activity of lateral septal neurons.

Corticotropin-releasing factor (CRF) has substantial effects on brain serotonergic activity, especially in limbic structures related to stress and anxiety. For example, relatively low doses of CRF administered into the dorsal raphe nucleus (DRN) decrease DRN unit activity and serotonin release in the lateral septum (LS), a limbic target of the DRN. In contrast, higher doses of CRF tend to be excitatory on both endpoints.