Challenges in preventing unions and pregnancies among adolescents in rural and Indigenous communities ruled by customs and traditions in Mexico.

Various Indigenous communities in Mexico establish their regulatory system according to their customs and traditions. In Chiapas, 27% of the population is Indigenous and has a high adolescent fertility rate. This study analyzes how customs and traditions influence unions and early pregnancies in specific contexts of rural and Indigenous communities.

Challenges of menstrual health: Knowledge and prejudices in Mexican public lower-secondary school female students.

A cross-sectional study describing aspects of menstrual poverty was analyzed with 201 female lower-secondary students in Mexico. The 15.5% indicated having a lot of knowledge about menstruation before experiencing it, increasing to 36.

Diminished placental Factor XIIIA1 expression associates with pre-conception antiretroviral treatment and preterm birth in pregnant people living with HIV.

We previously showed a link between maternal vascular malperfusion and pre-term birth (PTB) in pregnant people living with HIV (PPLH) initiating antiretroviral treatment (ART) before pregnancy, indicating poor placental vascularisation. After measuring antenatal plasma angiogenic factors to seek mechanistic insights, low levels of plasma Factor XIIIA1 (FXIIIA1) and vascular-endothelial-growth-factor (VEGF) was significantly associated with PTB at the time closest to delivery (median 34 weeks) in PPLH initiating ART before pregnancy. Knowing that FXIIIA1 is crucial for haemostasis, angiogenesis, implantation and pregnancy maintenance and that expression is found on placental macrophages (Hofbauer cells), we examined placentae at delivery from matching participants who either initiating ART before pregnancy or during gestation.

Drivers of urban biodiversity in Mexico and joint risks from future urban expansion, climate change, and urban heat island effect.

Urbanization is a phenomenon where humans concentrate in high densities and consume more per capita energy than in rural areas, imposing high pressures on biodiversity and ecosystem services. Although Mexico is recognized as a megadiverse country and there is an understanding of ecological and evolutionary processes underlying this high diversity, only some efforts have been devoted to understanding how urban biodiversity has been shaped. Here, we compiled a set of socioeconomic and ecological variables to explore macroecological patterns in urban biodiversity across Mexican municipalities.

"It should be hard to be a drug abuser" An evaluation of the criminalization of drug use in Sweden.

Background: Drug use was criminalized in Sweden in 1988 with aim of reducing the number of consumers and drug-related risks and harms. Imprisonment was introduced into the penalty scale in 1993 to improve the legislation's effectiveness. The criminalization has never been evaluated.

Development of New Drugs to Treat Tuberculosis Based on the Dinitrobenzamide Scaffold.

Tuberculosis (TB) continues to be a major global health challenge and a leading cause of death from infectious diseases. Inspired by the results from a previous work by our group on antimycobacterial -alkylnitrobenzamides, which are structurally related to the nitrobenzamide family of decaprenylphosphoryl-β-d-ribose oxidase (DprE1) inhibitors, the present study explored a broad array of substituted benzamides. We particularly focused on previously unexplored 3,5-dinitrobenzamide derivatives.

On the persistence of near-surface temperature dynamics in a warming world.

We consider issues related to the effect of climate change on the persistence of (trend-corrected) temperatures using global gridded data for both land and oceans. We first discuss how the presence of trends and additive noise affects inference about persistence. Ignoring a trend induces an upward bias, while not accounting for noise induces a downward bias.

Sexual and reproductive health among adolescents in vulnerable contexts in Mexico: Needs, knowledge, and rights.

Ensuring sexual and reproductive health, and rights for adolescents entails the prevention of early pregnancies, which are widely recognized as a public health problem. Based on the ecological model for early pregnancy, this article identifies the healthcare requirements for preventing unintended adolescent pregnancies in predominantly indigenous communities in Chiapas, Mexico. Using a convergent parallel mixed-methods study design, we surveyed adolescents (12-15 years old) and health personnel, organized focus groups with adolescents and their parents, and conducted in-depth interviews at the individual, family, school and community levels.

Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes.

Many neurodegenerative diseases involve amyloidogenic proteins forming surface-bound aggregates on anionic membranes, and the peptide amyloid β (Aβ) in Alzheimer's disease is one prominent example of this. Curcumin is a small polyphenolic molecule that provides an interesting opportunity to understand the fundamental mechanisms of membrane-mediated aggregation because it embeds into membranes to alter their structure while also altering Aβ aggregation in an aqueous environment. The purpose of this work was to understand interactions among curcumin, β-sheet-rich Aβ fibrillar oligomers (FO), and a model anionic membrane.

Phenotypic variation in leaf photosynthetic traits, leaf area index, and carbon discrimination of field-grown wheat genotypes and their relationship with yield performance in Mediterranean environments.

Leaf water potential, gas exchange, and chlorophyll fluorescence exhibited significant differences among genotypes, high environmental effects, but low heritability. The highest-yielding and drought-tolerant genotypes presented superior harvest index and grain weight, compared to drought-susceptible ones. Physiological phenotyping can help identify useful traits related to crop performance under water-limited conditions.

Assessing the Effect of the U.S. Vaccination Program on the Coronavirus Positivity Rate With a Multivariate Framework.

The factors influencing the incidence of COVID-19, including the impact of the vaccination programs, have been studied in the literature. Most studies focus on one or two factors, without considering their interactions, which is not enough to assess a vaccination program in a statistically robust manner. We examine the impact of the U.

Exploring plant responses to abiotic stress by contrasting spectral signature changes.

In this study, daily changes over a short period and diurnal progression of spectral reflectance at the leaf level were used to identify spring wheat genotypes ( L.) susceptible to adverse conditions. Four genotypes were grown in pots experiments under semi-controlled conditions in Chile and Spain.

Anthropogenic influence on extremes and risk hotspots.

Study of the frequency and magnitude of climate extremes as the world warms is of utmost importance, especially separating the influence of natural and anthropogenic forcing factors. Record-breaking temperature and precipitation events have been studied using event-attribution techniques. Here, we provide spatial and temporal observation-based analyses of the role of natural and anthropogenic factors, using state-of-the-art time series methods.

'TAVR Infected Pseudomonas Endocarditis': a case report.

Unlabelled: () rarely causes infective endocarditis (IE), previously reported for approximately 3% of all patients with IE. Most commonly, the infection occurs in intravenous drug users (IVDU) as right-sided endocarditis, noting presentations IE without history of intravenous drug to be extremely rare, finding only a few cases reported in the literature. However there are increasing reports of cardiovascular implantable electronic device-related and prosthetic heart valve infections caused by this pathogen in non-IVDUs.

Public policy on the prevention of subsequent adolescent pregnancy: what type of policy prevails?

This study aims to conduct a search of public-policy instruments seeking explicit references to subsequent adolescent pregnancy, as well as to discern what kinds of actions have been proposed as part of the international and national agendas to facilitate subsequent adolescent pregnancy prevention and care. During June 2021, we used an integrative review to search and to analyze national and international public policy instruments along with other documents related to subsequent adolescent pregnancy. We observed, for each, the presence of statements on subsequent adolescent pregnancy.

Toward New Epidemiological Landscapes of (Kinetoplastida, Trypanosomatidae) Transmission under Future Human-Modified Land Cover and Climatic Change in Mexico.

Chagas disease, caused by the protozoa , is an important yet neglected disease that represents a severe public health problem in the Americas. Although the alteration of natural habitats and climate change can favor the establishment of new transmission cycles for the compound effect of human-modified landscapes and current climate change on the transmission dynamics of has until now received little attention. A better understanding of the relationship between these factors and presence is an important step towards finding ways to mitigate the future impact of this disease on human communities.

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Objetivo: Identificar cómo se implementa la estrategia de anticoncepción posevento obstétrico (APEO) y analizar las barreras, acciones y recomendaciones para prevenir embara-zos subsecuentes en adolescentes. Material y métodos. Estudio cualitativo a través de análisis de contenido de 21 en-trevistas semiestructuradas a personal de salud de instituciones de atención a población sin seguridad social de la Ciudad de México y Morelos.

Trauma and latinx sexual- and gender-minority immigrants in the U.S.

Due to their multiple minoritized identities, Latinx sexual- and gender-minority immigrants risk exposure to various forms of traumatic stressors at home and abroad that can result in post-traumatic stress disorder and other comorbid problems like depression. A much-needed review and synthesis of the latest research highlights important factors for practitioners and scholars to consider relevant to this vulnerable and under researched population. A data-driven conceptualization helps identify risk factors across different points in time such as violence and discrimination from communal and institutional sources as well as acculturative and minority stressors.

Challenges for a Massive Implementation of Phenomics in Plant Breeding Programs.

Due to climate change and expected food shortage in the coming decades, not only will it be necessary to develop cultivars with greater tolerance to environmental stress, but it is also imperative to reduce breeding cycle time. In addition to yield evaluation, plant breeders resort to many sensory assessments and some others of intermediate complexity. However, to develop cultivars better adapted to current/future constraints, it is necessary to incorporate a new set of traits, such as morphophysiological and physicochemical attributes, information relevant to the successful selection of genotypes or parents.

The Campo de Dalias GNSS Network Unveils the Interaction between Roll-Back and Indentation Tectonics in the Gibraltar Arc.

The Gibraltar Arc includes the Betic and Rif Cordilleras surrounding the Alboran Sea; it is formed at the northwest-southeast Eurasia-Nubia convergent plate boundary in the westernmost Mediterranean. Since 2006, the Campo de Dalias GNSS network has monitored active tectonic deformation of the most seismically active area on the north coast of the Alboran Sea. Our results show that the residual deformation rates with respect to Eurasia range from 1.

Dopamine, Serotonin, and Structure/Function Brain Defects as Biological Bases for Treatment Response in Delusional Disorder: A Systematic Review of Cases and Cohort Studies.

Although blockade of dopamine receptors D2 and D3 appears to be the main mechanism of antipsychotic action, treatment response variability calls for an examination of other biological systems. Our aim is to systematically review reports of treatment response in delusional disorder (DD) in order to help determine its biological bases. Computerized searches of ClinicalTrials.

Impacts of land management and climate change in a developing and socioenvironmental challenging transboundary region.

Land-use/cover change is the major cause of terrestrial ecosystem degradation. However, its impacts will be exacerbated due to climate change and population growth, driving agricultural expansion because of higher demand of food and lower agricultural yields in some tropical areas. International strategies aimed to mitigate impacts of climate change and land use-cover change are challenging in developing regions.

Disentangling the trend in the warming of urban areas into global and local factors.

Large cities account for a significant share of national population and wealth, and exert high pressure on local and regional resources, exacerbating socioenvironmental risks. The replacement of natural landscapes with higher heat capacity materials because of urbanization and anthropogenic waste heat are some of the factors contributing to local climate change caused by the urban heat island (UHI) effect. Because of synergistic effects, local climate change can exacerbate the impacts of global warming in cities.