Requirement for Drosophila cytoplasmic tropomyosin in oskar mRNA localization.

The localization of oskar (osk) RNA to the posterior pole of the developing fruit fly (Drosophila) oocyte induces the assembly of pole plasm, causing development of the abdomen and germ line. Failure to localize oskar RNA results in embryos that lack abdomen and germ cells. Conversely, mis-targeting of oskar RNA to the anterior of the oocyte causes formation of ectopic abdomen and germ cells at the anterior pole.

Hypnotic hypermnesia: the empty set of hypermnesia.

Although a long tradition exists suggesting that hypnosis can enhance memory (hypnotic hypermnesia), the experimental literature is quite mixed. When, however, laboratory studies are classified according to the type of stimulus and memory tests employed, a remarkable orderliness of outcomes emerges: Recall tests for high-sense stimuli (e.g.

Evaluating hypnotic memory enhancement (hypermnesia and reminiscence) using multitrial forced recall.

Two experiments investigated whether hypnosis enhances memory retrieval per se or merely increases a person's willingness to report recollections. Both experiments assessed immediate and delayed (i.e.

The effect of response bias on recall performance, with some observations on processing bias.

We explored Roediger and Payne's proposal that response bias does not affect recall performance and that it is therefore not necessary to control for response productivity in recall studies. Two initial experiments, contrary to expectation, corroborated Roediger and Payne's findings: Forced recall did not produce more correct recalls than free recall, even though forced recall produced substantially more false alarms than did free recall. However, in succeeding experiments involving pictorial and verbal stimuli, reliable response-bias effects on recall were demonstrated.

Isolation and characterization of dominant female sterile mutations of Drosophila melanogaster. II. Mutations on the second chromosome.

Twenty-four, second chromosome, dominant female sterile (Fs) mutations in Drosophila are described. Fs(2) were isolated at a frequency of approximately 1 per 1000 EMS-treated chromosomes screened. In comparison the isolation of frequency for second chromosome zygotic recessive lethal mutations was approximately 550 per 1000.

Isolation and characterization of dominant female sterile mutations of Drosophila melanogaster. I. Mutations on the third chromosome.

Fifty-one dominant female sterile (Fs) mutations linked to the third chromosome of Drosophila melanogaster are described. EMS induced Fs mutations arise with the frequency of one Fs per about 2500 recessive lethals. Complementation analysis of the revertants showed that these Fs mutations represent 27-34 loci, about 60% of the third chromosome units mutable to dominant female sterility by EMS.

Function of torso in determining the terminal anlagen of the Drosophila embryo.

The formation of the unsegmented terminal regions of the Drosophila larva, acron and telson requires the function of at least five maternal genes (terminal genes class). In their absence, the telson and acron are not formed. One of them, torso (tor), has gain-of-function alleles which have an opposite phenotype to the lack-of-function (tor-) alleles: the segmented regions of the larval body, thorax and abdomen, are missing, whereas the acron is not affected and the telson is enlarged.

Characterization of Fs(2)1, a germ-line dependent dominant female sterile mutation of Drosophila.

Fs(2)1 is a germ-line dependent dominant female sterile mutation of Drosophila melanogaster. Fs(2)1 heterozygous females deposit very few abnormal eggs (collapsed, with malformed chorion). The degeneration of egg primorida starts around the end of egg maturation.

[Treatment of thoracic outlet syndrome following fracture of the clavicle with resection of the 1st rib (author's transl)].

The resection of the first rib with a transaxillary approach has been used in the operative treatment of this condition. This approach is though to have more advantages over the anterior (supraclavicular) or posterior (parascapular) ones. The segment resection of the middle third of clavicle would not seem to be justified in these cases.

Two-years' study with a combination of pindolol and clopamide ('Viskaldix') in patients with moderate hypertension.

A study was carried out to evaluate the long-term effects and side-effects of a combination product containing the beta-blocker pindolol (10 mg) and the diuretic clopamide (5 mg) in 15 patients with moderate hypertension. All patients completed the 2-years' study. The dose of the combination was increased until blood pressure normalized or a maximum dose of 3 tablets (equivalent to 30 mg pindolol and 15 mg clopamide) daily was reached.

Hypermnesia for Socratic stimuli: The growth of recall for an internally generated memory list abstracted from a series of riddles.

Hypermnesia (the increase of recall with time and effort) was tested and contrasted for three conditions of input, each thought to involve different levels of cognitive processing. The basic design involved a multitrial free recall procedure, with groups differing only in the presentation of materials to be remembered. The words subjects (most superficial cognitive processing) recalled a serial list of 40 words; the pictures subjects recalled the same series of 40 pictures; and the Socratic subjects (deepest cognitive processing) recalled an internally generated memory set consisting of covert solutions to 40 riddles, which had been pretested to yield the same 40 items as those of the other groups.