Neonatal hematogenous osteomyelitis: risk factors for long-term sequelae.

The findings in 40 infants with neonatal osteomyelitis were examined to evaluate factors that may predict the development of sequelae. On follow-up at 1-11 years of age, 16 children were found to have moderate (six) and severe (10) sequelae. Thirteen of these 16 children were among the 21 infants who had perinatal risk factors.

Neonatal osteomyelitis. Radiographic findings and prognosis in relation to site of involvement.

Forty patients with hematogenous osteomyelitis in the neonatal period were followed up for one to 11 years. Early symptoms and radiographic abnormalities are described and the importance of early diagnosis and early treatment is emphasized. Course and sequelae are discussed in relation to different sites of involvement.

Vesicoureteric reflux and pyelonephritis. Long time effect on area of renal parenchyma.

The effect of gross vesicoureteric reflux in combination with urinary tract infection on the area of the renal parenchyma was analysed in 8, non-selected, girls during 3 to 6 years. A progressive significant decrease of the relative size of the kidneys with vesicoureteric reflux occurred as compared with that of kidneys with normal ureters. The decrease was mainly due to scars in the upper and lower poles.

Birth injuries to the epiphyseal cartilage.

A birth injury in the vicinity of a joint might lead to a fracture through the epiphyseal cartilage. The criteria for diagnosing such a fracture at radiography are considered and the continued remodelling of the bone demonstrated. The history of 2 cases with late diagnosis and serious long-term sequelae are described, in order to emphasize the necessity of early radiography.

Relationship between area and function of the kidney in well defined childhood nephropathies.

Length, parenchymal area planimetrically determined and volume of the kidney were estimated at urography and related to glomerular filtration rate in patients with different nephropathies. The results demonstrate that the size of the kidney is an excellent index of renal function in patients with pyelonephritic scarring secondary to urinary tract infection and vesicoureteral reflux. It is also a good index in patients with obstructive hydronephrosis but a poor index in patients with glomerulonephritis.