Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross.

Mainstay treatment for Plasmodium vivax malaria has long relied on chloroquine (CQ) against blood-stage parasites plus primaquine against dormant liver-stage forms (hypnozoites), however drug resistance confronts this regimen and threatens malaria control programs. Understanding the basis of P. vivax chloroquine resistance (CQR) will inform drug discovery and malaria control.

Impact of Trauma Hospital Ransomware Attack on Surgical Residency Training.

Background: A recent ransomware attack led to the shutdown of the electronic health information system (HIS) at our trauma center for 2 mo. We investigated its impact on residency training during the downtime.

Material And Methods: General and orthopedic surgical residents who rotated at the hospital were invited to participate in a survey regarding their patient care and residency training experiences during the downtime.

Interprofessional Communication Goes Up When the Electronic Health Record Goes Down.

Objective: The electronic health record (EHR) has been faulted for the erosion of interprofessional communication and the patient-physician relationship. Surgical residents may be susceptible to communication workarounds facilitated by the EHR, but the full extent is not well understood. A recent ransomware attack with the abrupt return to paper charting provided a unique opportunity to investigate the impact of the EHR on surgical residents' interprofessional communication.

The Lattice Spacing Variability of Intrinsic Float-Zone Silicon.

Precision lattice spacing comparison measurements at the National Institute of Standards and Technology (NIST) provide traceability of X-ray wavelength and powder diffraction standards to the international system of units (SI). Here, we both summarize and document key measurements from the last two decades on six lots of intrinsic float-zone silicon, including unpublished results and recent internal-consistency checks. The comparison measurements link the unknown lattice spacing of a test crystal to a standard crystal for which the lattice spacing has been accurately determined by X-ray/optical interferometry in units traceable to the definition of the meter.

Nipple-Sparing Mastectomy via an Inframammary Fold Incision with Implant-Based Reconstruction in Patients with Prior Cosmetic Breast Surgery.

Background: Nipple-sparing mastectomy through an inframammary fold incision (NSM-IMF) with implant-based reconstruction (IBR) is a cosmetically preferable approach to breast cancer treatment in appropriate candidates. However, patients who have undergone prior cosmetic breast surgery (CBS) may be at increased risk for postoperative complications secondary to existing surgical scars.

Objective: To assess whether prior CBS increases the risk of complications following NSM-IMF with IBR.

World Year of Physics: a direct test of E=mc2.

One of the most striking predictions of Einstein's special theory of relativity is also perhaps the best known formula in all of science: E=mc(2). If this equation were found to be even slightly incorrect, the impact would be enormous--given the degree to which special relativity is woven into the theoretical fabric of modern physics and into everyday applications such as global positioning systems. Here we test this mass-energy relationship directly by combining very accurate measurements of atomic-mass difference, Delta(m), and of gamma-ray wavelengths to determine E, the nuclear binding energy, for isotopes of silicon and sulphur.

Precision Measurement of Fundamental Constants Using GAMS4.

We discuss the connection of high-energy gamma-ray measurements with precision atomic mass determinations. These rather different technologies, properly combined, are shown to lead to new values for the neutron mass and the molar Planck constant. We then proceed to describe the gamma-ray measurement process using the GAMS4 facility at the Institut Laue-Langevin and its application to a recent measurement of the 2.

A curved crystal spectrometer for energy calibration and spectral characterization of mammographic x-ray sources.

Clinical efficacy of diagnostic radiology for mammographic examinations is critically dependent on source characteristics, detection efficiency, image resolution and applied high voltage. In this report we focus on means for evaluation of source-dependent issues including noninvasive determination of the applied high voltage, and characterization of intrinsic spectral distributions which in turn reflect the effects of added filtration and target and window contamination. It is shown that a particular form of x-ray curved crystal spectrometry with electronic imaging can serve to determine all relevant parameters within the confines of a standard clinical exposure.

Erratum: Precision Comparison of the Lattice Parameters of Silicon Monocrystals.

[This corrects the article on p. 1 in vol. 99.

Precision Comparison of the Lattice Parameters of Silicon Monocrystals.

The lattice spacing comparator established at the National Institute of Standards and Technology to measure the lattice spacing differences between nearly perfect crystals is described in detail. Lattice spacing differences are inferred from the measured differences in Bragg angles for different crystals. The comparator is a two crystal spectrometer used in the nearly nondispersive geometry.

Description, performance, and wavelengths of iodine stabilized lasers.

A description is given of lasers stabilized to components of the (129)I(2) spectrum in the region of the 633-nm laser lines for (3)He-(20)Ne and (3)He-(22)Ne. Relationships between operational characteristics such as power output, peak size, and peak width are shown, along with their relationships to some of the controllable parameters such as excitation level, iodine absorption, and iodine pressure. We found an iodine pressure broadening of about 13 MHz/Torr with a 2.