Sepsis negatively affects capillary function and oxygen delivery, potentially worsening patient outcomes.
Lower levels of immunoglobulin G2 do not contribute to severe flu complications, suggesting other factors may play a role in flu severity.
New research indicates that intravenous immunoglobulin may provide brain protection during sepsis by blocking harmful immune responses such as complement activation and apoptosis. *
The study assessed the incidence of pneumonia in a cohort of systemic lupus erythematosus (SLE) patients and identified key risk factors.
Thirty-six out of 232 SLE patients experienced at least one pneumonia event, leading to a standardized incidence ratio of 5.1, indicating a significantly higher rate of pneumonia compared to the general population.
Factors linked to pneumonia in SLE patients included disease severity, specific genetic variants (notably the FCGR2A HH genotype), and a history of hospital admissions, even after adjusting for prior immunosuppressive treatment.