Publications by authors named "E von der Lippe"

Article Synopsis
  • The Burden of Disease (BOD) approach, starting from the Global Burden of Disease study in the 1990s, aims to enhance monitoring of population health but faces challenges due to inconsistencies in DALY metric reporting.
  • To address these issues, the STROBOD statement was developed to standardize the reporting of DALY calculation studies, consisting of 28 items in six sections for improved transparency and comparability.
  • The initial STROBOD statement serves as a framework for BOD research, with plans for continuous evaluation and potential specialized checklists in future versions to cater to specific applications like injury or risk factor estimation.
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Background: Health inequalities have been associated with shorter lifespans. We aimed to investigate subnational geographical inequalities in all-cause years of life lost (YLLs) and the association between YLLs and socioeconomic factors, such as household income, risk of poverty, and educational attainment, in countries within the European Economic Area (EEA) before the COVID-19 pandemic.

Methods: In this ecological study, we extracted demographic and socioeconomic data from Eurostat for 1390 small regions and 285 basic regions for 32 countries in the EEA, which was complemented by a time-trend analysis of subnational regions within the EEA.

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Background: Several studies report lack of meropenem pharmacokinetic/pharmacodynamic (PK/PD) target attainment (TA) and risk of therapeutic failure with intermittent bolus infusions in intensive care unit (ICU) patients. The aim of this study was to describe meropenem TA in an ICU population and the clinical response in the first 72 h after therapy initiation.

Methods: A prospective observational study of ICU patients ≥18 years was conducted from 2014 to 2017.

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Background: Although overall health status in the last decades improved, health inequalities due to non-communicable diseases (NCDs) persist between and within European countries. There is a lack of studies giving insights into health inequalities related to NCDs in the European Economic Area (EEA) countries. Therefore, the aim of the present study was to quantify health inequalities in age-standardized disability adjusted life years (DALY) rates for NCDs overall and 12 specific NCDs across 30 EEA countries between 1990 and 2019.

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Objectives: Within the framework of the burden of disease (BoD) approach, disease and injury burden estimates attributable to risk factors are a useful guide for policy formulation and priority setting in disease prevention. Considering the important differences in methods, and their impact on burden estimates, we conducted a scoping literature review to: (1) map the BoD assessments including risk factors performed across Europe; and (2) identify the methodological choices in comparative risk assessment (CRA) and risk assessment methods.

Methods: We searched multiple literature databases, including grey literature websites and targeted public health agencies websites.

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