Publications by authors named "E van der Schoot"
Moths and other insects are attracted by artificial light sources. This flight-to-light behaviour disrupts their general activity focused on finding resources, such as mating partners, and increases predation risk. It thus has substantial fitness costs.
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- Fetal and neonatal alloimmune thrombocytopenia (FNAIT) can cause serious complications like intracranial bleeding, but its prevalence in pregnancies isn't fully understood, leading to no standard screening procedures.
- A study analyzed the occurrence of clinically detectable FNAIT among HPA-1a-immunised women by monitoring a group of 913 HPA-1a-negative pregnant women who underwent routine antibody screening.
- Out of these, only one case of severe FNAIT was found (1.2%), alongside three cases of mild FNAIT (3.7%), indicating that while FNAIT is rare, it still poses risks that need further investigation for better screening methods.
Background: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a condition during pregnancy, which can lead to thrombocytopenia and a bleeding tendency with intracranial hemorrhage (ICH) being the most concerning complication in the fetus or neonate. An incompatibility between human platelet antigen (HPA)-1a accounts for the majority of FNAIT cases. Binding of HPA-1a-specific alloantibodies to their target on fetal platelets and endothelial cells can induce apoptosis of megakaryocytes, disrupt platelet function, and impair angiogenesis.
View Article and Find Full Text PDFBackground And Aims: Solid tumors account for about 30% of all pediatric cancers. The diagnosis is typically based on histological and molecular analysis of a primary tumor biopsy. Liquid biopsies carry several advantages over conventional tissue biopsy.
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