Publications by authors named "E van Heurn"
Article Synopsis
- Sacrococcygeal teratoma (SCT) is a rare congenital tumor with unclear risks of malignancy and recurrence, prompting a study to better understand these factors.
- A global retrospective cohort study analyzed data from 3,612 SCT patients across 145 institutes in 62 countries, focusing on malignant transformation and recurrence rates.
- Results showed that the risk of malignancy increases with age, plateauing at six years, while 10.2% of patients experienced recurrence, with significant associations related to tumor type and initial histology.
Background: Infants presenting with unexpected pneumoperitoneum upon abdominal X-ray, indicating a gastrointestinal perforation (GIP), have a surgical emergency with potential morbidity and mortality. Preoperative determination of the location of perforation is challenging but will aid the surgeon in optimizing the surgical strategy, as colon perforations are more challenging than small bowel perforations. Therefore, the aim of this study is to provide an overview of preoperative patient characteristics, determine the differences between the small bowel and colon, and determine underlying causes in a cohort of infants with unexpected GIP.
View Article and Find Full Text PDFBackground: Hirschsprung disease is a congenital intestinal motility disorder characterized by an absence of enteric ganglion cells. Total colonic aganglionosis and near total or total intestinal aganglionosis, defined as absence of ganglion cells in the entire colon and with variable length of small bowel involved, are life-threatening conditions which affect less than 10 % of all patients with Hirschsprung disease. The aim of this project was to develop clinical consensus statements within ERNICA, the European Reference Network for rare congenital digestive diseases, on four major topics: Surgical treatment of total colonic aganglionosis, surgical treatment of total intestinal aganglionosis, management of poor bowel function in total colonic and/or intestinal aganglionosis and long-term management in total colonic and or intestinal aganglionosis.
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- Open inguinal hernia repair is the traditional treatment for children, but laparoscopic methods are becoming more popular, though there's no clear consensus on which is better due to varying study outcomes.
- A core outcome set (COS) will be developed to standardize the measurement and reporting of outcomes across studies, addressing the current inconsistencies.
- The project involves identifying relevant outcome domains, conducting a Delphi study to prioritize outcomes, and holding an expert meeting to finalize the COS and its implementation strategies.
Background And Aims: Although appendicitis is rare in young infants, the reported mortality is high. Primary aim of this systematic review was to provide updated insights in the mortality and morbidity (postoperative complications, Clavien-Dindo grades I-IV) of appendicitis in infants ≤3 months of age. Secondary aims comprised the evaluation of patient characteristics, diagnostic work-up, treatment strategies, comorbidity, and factors associated with poor outcome.
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