Publications by authors named "E van Emmen"
Molecular detection of SARS-COV-2 in exhaled breath at the point-of-need.
Biosens Bioelectron
December 2022
The SARS-CoV-2 pandemic has highlighted the need for improved technologies to help control the spread of contagious pathogens. While rapid point-of-need testing plays a key role in strategies to rapidly identify and isolate infectious patients, current test approaches have significant shortcomings related to assay limitations and sample type. Direct quantification of viral shedding in exhaled particles may offer a better rapid testing approach, since SARS-CoV-2 is believed to spread mainly by aerosols.
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- - Four newborns, one girl and three boys, were diagnosed with different skin conditions: feeding blisters, bullous impetigo, erythema toxicum neonatorum, and transient neonatal pustular melanosis.
- - The baby with bullous impetigo received antibiotic treatment, while the others had no treatment and recovered well, though the one with transient neonatal pustular melanosis showed some hyperpigmentation.
- - Neonatal skin eruptions are common and mostly harmless, but it's crucial to identify and treat certain conditions quickly through a detailed history and clinical observation, and skin cultures can aid in diagnosis.
Objective: We measured surfactant phosphatidylcholine (PC) pool size and half-life in human congenital diaphragmatic hernia (CDH) patients who required extracorporeal membrane oxygenation (ECMO). Study design Surfactant PC pool size and half-life were measured by endotracheal administration of deuterium-labeled dipalmitoylphosphatidylcholine in 8 neonates with CDH on ECMO (CDH-ECMO), in 7 neonates with meconium aspiration syndrome on ECMO (MAS-ECMO), and in 6 ventilated infants (NON-ECMO).
Results: Lung PC pool size in the CDH-ECMO group was 73 +/- 17 mg/kg (mean +/- SEM), which was not significantly different from the MAS-ECMO (50 +/- 18 mg/kg) and the NON-ECMO group (69 +/- 38 mg/kg).