Publications by authors named "E de Clavijo"
Introduction And Objectives: To identify risk factors associated with the development of hepatocellular carcinoma (HCC) in an unselected cohort of patients with chronic B virus infection (CHB) in Spain. A predictive model was developed to assess the risk of HCC.
Material And Methods: A prospective open-cohort study recruited 446 unselected patients with chronic hepatitis B infection from two hospitals in Málaga (Spain).
Article Synopsis
- - A 27-year-old man with recurrent pancreatitis was found to have a rare genetic mutation (homozygous SPINK1 N34S) after multiple hospitalizations and diagnostic testing.
- - After unsuccessful endoscopic treatments, he underwent a laparoscopic Puestow procedure to improve his symptoms and pancreatic drainage.
- - His recovery was successful, and he was discharged with enzyme therapy, highlighting the complexities of diagnosing and managing hereditary pancreatitis linked to genetic factors.
Background: Since the introduction of direct-acting antivirals, thousands of chronic hepatitis C patients have been successfully treated. However, vulnerable populations have a higher prevalence of hepatitis C virus (HCV) infection and face barriers that impede their access to antivirals. We carried out an HCV microelimination program focused on vulnerable population groups in Malaga.
View Article and Find Full Text PDFUnusual Surge of Acute Hepatitis A Cases in 2016 and 2017 in Malaga, Southern Spain: Characterization and Relationship with Other Concurrent European Outbreaks.
J Clin Med
October 2023
We aimed to describe the Hepatitis A virus (HAV) cases that arose in Malaga (Spain) in 2016 and 2017 when the European Centre for Disease Prevention and Control (ECDC) reported several outbreaks among men who have sex with men (MSM). Therefore, we conducted a retrospective study gathering demographic, clinical, and immunological data from the acute HAV patients attending our hospital between March 2016 and December 2017. Additionally, VP1/P2A region was amplified from serum samples, sequenced, and genotyped.
View Article and Find Full Text PDFArticle Synopsis
- This study investigates the prevalence and impact of Hepatitis E virus (HEV) in patients initially thought to have drug-induced liver injury (DILI) in Spain.
- Researchers analyzed 265 patients with suspected DILI and 108 control subjects, finding 8% of patients tested positive for acute HEV infections and a 35% overall seroprevalence of anti-HEV antibodies.
- The findings suggest that active HEV infection should be evaluated in suspected DILI cases, especially for those with pre-existing liver conditions and significantly elevated liver enzymes.