Allele Frequencies and Forensic Data of 25 STR Markers for Individuals in Northeast Brazil.

Identifying DNA markers such as Short Tandem Repeats (STR) can be used to investigate genetic diversity based on levels of heterozygosity within and between populations. Allele frequencies and forensic data for STRs were obtained from a sample of 384 unrelated individuals living in Bahia, Northeastern Brazil. Thus, the present study aimed to identify the allele frequency distribution, in addition to the forensic and genetic data, of 25 STR loci in the population of Bahia.

Solifenacin: scientific evidence in the treatment of overactive bladder.

Objectives: This article aims to analyse the use of solifenacin in the treatment of overactive bladder in order to show its efficacy and safety within the framework of the scientific evidence.

Methods: The available scientific literature was reviewed, including most of the relevant clinical trials performed with solifenacin.

Results: All the studies analysed show significant improvements in patients treated with solifenacin versus placebo and tolterodine.