Antibiotic-Resistant E. coli in Uncomplicated Community-Acquired Urinary Tract Infection.

Background: Routine urine culture testing is not recommended for uncomplicated urinary tract infections (UTIs). As a result, the antibiotic resistance patterns or the organisms causing UTIs are not adequately reflected in routine data. We studied the sensitivity of Escherichia coli (E.

[Effective management of an outbreak with multiresistent Klebsiella pneumoniae in a neurorehabilitation unit].

Background: In addition to acute care hospitals, rehabilitation centres are increasingly confronted with multi-resistant pathogens. Long durations of stay and intensive treatments impose special hygienic challenges.

Material And Methods: We investigated an extended spectrum beta-lactamase-Klebsiella pneumoniae (ESBL-K.

Whole Genome Sequence Analysis of CTX-M-15 Producing Isolates Allowed Dissecting a Polyclonal Outbreak Scenario.

Extended-spectrum β-lactamase (ESBL) producing pose an important threat of infection with increased morbidity and mortality, especially for immunocompromised patients. Here, we use the rise of multidrug-resistant in a German neurorehabilitation center from April 2015 to April 2016 to dissect the benefit of whole genome sequencing (WGS) for outbreak analyses. In total, 53 isolates were obtained from 52 patients and examined using WGS.

Bacterial translocation during graft-versus-host disease after small bowel transplantation is reduced following inhibition of inducible nitric oxide synthesis.

Background: Increased nitric oxide (NO) production may contribute to intestinal barrier dysfunction and increased bacterial translocation (BT). Since BT may play a major role in graft-versus-host disease (GVHD) after small bowel transplantation (SBTx), we evaluated the role of NO production in GVHD after SBTX in the rat.

Methods: Using the standard model of semiallogeneic SBTx in the rat, we prepared three experimental groups.