Publications by authors named "E Zamora Madaria"
Acute Pancreatitis: An Update of Evidence-Based Management and Recent Trends in Treatment Strategies.
United European Gastroenterol J
January 2025
Acute pancreatitis is a common gastrointestinal disease leading to hospitalisation. Recent advancements in its management have primarily focussed on the development of early phase medical interventions targeting inflammatory pathways, optimisation of supportive treatment (including fluid resuscitation, pain management and nutritional management), appropriate use of antibiotics, implementation of minimally invasive interventions for infected necrosis, and the necessity of follow-up for long-term complications. These advancements have significantly improved personalised management and overall outcomes of acute pancreatitis.
View Article and Find Full Text PDFCorrection: Normal saline versus lactated Ringer's solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial study protocol.
Trials
November 2024
Background: No specific triglyceride-lowering therapy is recommended in patients with hypertriglyceridemia-associated acute pancreatitis (HTG-AP), primarily because of the lack of quality evidence. This study aimed to describe practice variations in triglyceride-lowering therapies for early HTG-AP patients and assess whether more rapid triglyceride decline is associated with improving organ failure.
Methods: This is a multicentre, prospective cohort study recruiting HTG-AP patients with elevated plasma triglyceride (> 11.
Article Synopsis
- This narrative review focuses on idiopathic acute pancreatitis (IAP), discussing its epidemiology, diagnosis, clinical course, and treatment over the last decade.
- The study aims to unify evidence on diagnosing acute pancreatitis (AP) due to the lack of a validated protocol, which could help reduce recurrent episodes and improve patient outcomes.
- Findings highlight significant variations in AP aetiology and diagnostics across studies and regions, while proposing a new diagnostic algorithm and emphasizing the need for more research on advanced testing and treatment for IAP.