Publications by authors named "E Z Ustinova"
Vascularization of bioengineered bone tissue constructs remains a challenging problem of regenerative medicine. Spheroids generated in 3D culture of adipose-derived stromal cells supplemented with inducing factors demonstrate stable characteristics and express of mesenchymal, endothelial, and osteoblasts markers, and represent a prototype of vascularized microtissue. Adipose-derived stromal cells spheroids induced to both angio- and osteogenic differentiation can be used in development of new innovative technologies for in vitro fabrication of vascularized bioequivalents for repair of large bone defects.
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- Researchers are exploring new ways to use stem cells to heal damaged eye tissues, focusing on an area called the limbal eye zone that has lots of these stem cells.
- The study looks at creating special 3D structures, called spheroids, from limbal stem cells that can help them work better together.
- These 3D spheroids help keep the stem cells in a special state that allows them to heal both the front and possibly the back parts of the eye.
The implementation of principles of highly sensitive flow cytometry into diagnostic of paroxysmal nocturnal hemoglobinuria increased rate of detection of paroxysmal nocturnal hemoglobinuria clone in patients with aplastic anemia already at early stages of diagnosis establishment (up to 79%). However, detection of paroxysmal nocturnal hemoglobinuria clone attracts interest not only from point of view of progression in % of patients with aplastic anemia). The occurrence of paroxysmal nocturnal hemoglobinuria clone in patients with aplastic anemia can be accompanied by hidden disorders of haemopoesis with increasing risk in conditions of proliferative stress.
View Article and Find Full Text PDFObjective: This case demonstrates the difficulty of diagnostics of oxalate nephropathy and possibility of development of acute kidney injury.
Summary: The paper describes a patient with oxalate nephropathy and acute kidney injury. Specific features of oxalate diathesis are discussed as well as approaches to its diagnosis.