Publications by authors named "E Yu Kirichenko"
Hydrogen sulfide (HS) donors are emerging as promising candidates for neuroprotective agents. However, HS-dependent neuroprotective mechanisms are not yet fully understood. We have demonstrated that an HS donor (sodium sulfide, NaS) reduces the expression of inducible NO synthase (iNOS) and amyloid-beta precursor protein (APP) in damaged neural tissue at 24 h and 7 days following traumatic brain injury (TBI).
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- - Gap junctions are channels that allow communication between adjacent cells, but their role in brain tumors, particularly glioblastoma multiforme (GBM), is not well understood.
- - Research shows that the protein Connexin 43 (Cx43) and the polyamine spermine are co-expressed in human GBM samples, implying they might work together in tumor development and integration into surrounding neural networks.
- - The study utilized various microscopy techniques to demonstrate that Cx43 and spermine localize in specific regions of GBM, indicating that they may facilitate gap junction activity, which could enable tumor cells to share metabolic products with neighboring cells.
We study the synergy between disorder (phenomenologically modeled by the introduction of Riesz fractional derivative in the corresponding Schrödinger equation) and spin-orbit coupling (SOC) on the exciton spectra in two-dimensional (2D) semiconductor structures. We demonstrate that the joint impact of "fractionality" and SOC considerably modifies the spectrum of corresponding "ordinary" (i.e.
View Article and Find Full Text PDFAdaptation and functional significance of chlorophyll deficit in the light green leaf sectors of variegated plants are little known. Efficiency of photosystem II for dark and light adapted states (F/F and ΔF/F') and fluorescence decrease rates (R) of light green leaf sectors of Dracaena fragrans L. were studied by methods of PAM-fluorometry and video registration.
View Article and Find Full Text PDFModifications of mRNA, especially methylation of adenosine, have recently drawn much attention. The much rarer modification, 5-hydroxymethylation of cytosine (5hmC), is not well understood and is the subject of this study. Vertebrate Tet proteins are 5-methylcytosine (5mC) hydroxylases and catalyze the transition of 5mC to 5hmC in DNA.
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