Effects of 1-methylcyclopropene, methyl jasmonate and salicylic acid on physicochemical properties and wooliness of nectarine fruit during cold storage.

Background: Owing to its high perishability, the market life of nectarine fruit is very short. Cold storage is a principal approach to limit post-harvest quality loss in nectarines. The objective of this research was to evaluate the impact of postharvest methyl jasmonate (MeJA), salicylic acid (SA) and 1-methylcyclopropene (1-MCP) on quality properties of nectarine fruit, specifically weight loss, firmness, phenolics and antioxidant activity, following cold storage and subsequent shelf life.

Risk factors for neurologic sequelae in children and adolescents with hemophilia after intracranial hemorrhage.

Background: Intracranial hemorrhage (ICH) is reportedly rare but has high morbidity and mortality risk in persons with hemophilia. Although the risk factors that facilitate bleeding are known, the factors affecting the sequelae are not well known.

Objectives: We planned to investigate the risk factors for neurologic sequelae in children and adolescents with hemophilia suffering from ICH.

Predicting Severe Respiratory Failure in Patients with COVID-19: A Machine Learning Approach.

Studies attempting to predict the development of severe respiratory failure in patients with a COVID-19 infection using machine learning algorithms have yielded different results due to differences in variable selection. We aimed to predict the development of severe respiratory failure, defined as the need for high-flow oxygen support, continuous positive airway pressure, or mechanical ventilation, in patients with COVID-19, using machine learning algorithms to identify the most important variables in achieving this prediction. This retrospective, cross-sectional study included COVID-19 patients with mild respiratory failure (mostly receiving oxygen through a mask or nasal cannula).

Medical device-related pressure injuries: The mediating role of attitude in the relationship between ICU nurses' knowledge levels and self-efficacy.

Aim: This study examines the mediating role of attitude towards preventing pressure injuries (PIs) in the effect of knowledge about Medical Device-Related Pressure Injuries (MDRPI) on self-efficacy in PI management among Turkish intensive care unit (ICU) nurses.

Materials And Methods: A descriptive, cross-sectional study was conducted with 302 ICU nurses in Turkey from October 15, 2023, to April 30, 2024. Data were collected using the Nurse Information Form, Medical Device Related Pressure Injury Knowledge Assessment Test (MDRPI-KAT), Attitude towards Pressure Ulcer Prevention Instrument (APuP), and the Pressure Ulcer Management Self-Efficiency Scale (PUMSES).

Gold nanoparticles decorated FOLFIRINOX loaded liposomes for synergistic therapy of pancreatic cancer.

Pancreatic cancer is predicted to be the second highest cause of cancer deaths by 2030, with a mortality rate of 98 % and a 5-year survival rate of only 4-8 %. FOLFIRINOX which consists of four main ingredients has shown superior efficacy in treating patients with pancreatic cancer compared to other agents and combinations. However, toxicities have prevented full-dose use of FOLFIRINOX.