Publications by authors named "E Wyffels"

Article Synopsis
  • The study examines gender differences in the relationship between angiographic findings and fractional flow reserve (FFR) in patients with coronary stenosis.
  • Median FFR values were found to be higher in female patients than in male patients, and a 50% diameter stenosis (DS) is identified as the best threshold for detecting ischemic FFR in both genders.
  • While a higher DS threshold (≥ 59%) improves lesion classification in females, it also results in a higher rate of false negatives.
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Article Synopsis
  • Robotic-assisted coronary interventions (R-PCI) have shown safety and effectiveness in treating various coronary lesions, but their real-world clinical outcomes remain unclear.
  • A study evaluated 111 patients to assess major adverse cardiovascular events (MACE) and found a low occurrence of 5.4% during a median follow-up period.
  • The research indicated that while procedural complexity increased time and radiation exposure, it did not impact in-hospital or long-term outcomes, and CCTA-guided procedures allowed for a higher rate of same-day discharge (64.6% vs. 44.2%).
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This analysis of real-world data examines the efficacy, safety, and long-term outcomes of renal denervation in hypertensive patients for up to 10 years. Sixty-five consecutive patients underwent renal denervation (RDN) (single operator) for uncontrolled resistant hypertension. Efficacy was defined as the interindividual change of office (OBPM) and ambulatory blood pressure monitoring (ABPM) at 1, 6, 12 months, 2-4 and 5-10 years after RDN.

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Background: Discrepancies between stenosis severity assessed at coronary computed tomography angiography (CCTA) and ischemia might depend on vessel type. Coronary plaque features are associated with ischemia. Thus, we evaluated the vessel-specific correlation of CCTA-derived diameter stenosis (DS) and invasive fractional flow reserve (FFR) and explored whether integrating morphological plaque features stratified by vessel might increase the predictive yield in identifying vessel-specific ischemia.

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Article Synopsis
  • Severe aortic stenosis (AS) leads to changes in the heart’s left ventricle and can affect blood flow and resistance in coronary arteries.
  • A study assessed coronary blood flow and microvascular resistance in AS patients before and after transcatheter aortic valve implantation (TAVI) and found no immediate changes right after the procedure.
  • Six months post-TAVI, patients showed significant improvement in hyperaemic perfusion, indicating that over time, left ventricular remodelling positively affected blood flow during increased demand.
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