Publications by authors named "E Wender-Ozegowska"

Article Synopsis
  • - Exposure to maternal diabetes during pregnancy can lead to complications for both the mother and the baby, as well as increase the risk of chronic diseases for the child later in life.
  • - Animal models are used to clarify the cause-and-effect relationship between maternal diabetes and long-term health outcomes for offspring, allowing researchers to minimize misleading variables.
  • - This study aims to systematically analyze the long-term complications in offspring linked to maternal diabetes, combining insights from human and animal studies to explore new avenues for preventing and treating high blood sugar during pregnancy.
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Article Synopsis
  • The study investigates how glucose transporter proteins (GLUTs) in the placenta are expressed in pregnant women with type 1 diabetes, early gestational diabetes (eGDM), and healthy controls, aiming to find correlations with clinical parameters.
  • Significant decreases in GLUT-3 and GLUT-4 mRNA expression were observed in patients with diabetes, especially eGDM, and these changes were linked to lower neonatal birth weights and various glycemic factors.
  • The research also uncovered substantial transcriptomic changes in women with diabetes, indicating a complex relationship between GLUT expression, neonatal outcomes, and glycemic control.
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Parvovirus B19 is a virus that causes a common and usually harmless infection in both children and adults. If the virus is transmitted transplacentally during pregnancy, it can have serious consequences for both the pregnant woman and the fetus. Potential complications include severe fetal anemia, which can lead to intrauterine fetal death.

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The aim of the study was to investigate the relation between thyroid autoimmunity (TAI), reflected as the presence of thyroid peroxidase antibodies (TPOAb), and parameters of ovarian reserve in women with type 1 diabetes (T1DM) and polycystic ovary syndrome (PCOS). We studied 83 euthyroid women with T1DM (age - 26 ± 5 years, BMI - 24 ± 3 kg/m) - 12 with PCOS and positive TPOAb (PCOS + TPOAb), 29 with PCOS with negative TPOAb (PCOS + noTPOAb), 18 without PCOS with positive TPOAb (noPCOS + TPOAb), 24 without PCOS with negative TPOAb (noPCOS + noTPOAb). Serum concentrations of anti-Müllerian hormone (AMH), sex hormones, TSH, thyroid hormones and TPOAb were assessed.

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