Publications by authors named "E Wayne Massey"
Red blood cell (RBC) antigen matching beyond ABO and RhD is commonly recommended for patients with sickle cell disease (SCD) and thalassaemia. We present an updated systematic literature review to inform evidence-based guidelines on RBC matching. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) tool was used to develop recommendations.
View Article and Find Full Text PDFAims: Healthcare professionals are relevant stakeholders because of their gatekeeper role in the clinic. This study aims to explore their perspectives on the potential future clinical implementation of the bio-artificial pancreas (BAP) for people with type 1 diabetes, and suitable target groups.
Methods: Semi-structured interviews were conducted with 17 healthcare professionals, including endocrinologists, nurses, and pancreas transplant surgeons.
As opioid-related overdose emergency department visits continue to rise in the United States, there is a need to understand the location and magnitude of the crisis, especially in at-risk rural areas. We analyzed sets of ZIP code level electronic health records for emergency department visits from 6 hospitals for two rural regions of Maryland with higher opioid-related overdose rates. Analysis of the demographics of visits found Black or African American emergency department visits in both rural regions were higher than the proportion of their population per region.
View Article and Find Full Text PDFBackground: The development of a hybrid beta-cell replacement approach, referred to as a personalized, transplantable bioartificial pancreas (BAP), holds promise to treat type 1 diabetes (T1D). This interview study aimed to explore patients' expectations, needs, concerns, and considerations when considering to undergo a BAP transplantation.
Research Design And Methods: Semistructured interviews were conducted with 24 participants diagnosed with T1D.
Article Synopsis
- Valid measurement of drug use in clinical trials for substance use disorder is crucial for assessing outcomes, and while self-reports are common, their accuracy varies.
- This study compared self-reports and urinalysis in a methadone treatment program and found that urinalysis often detected more drug use than participants reported, except for heroin.
- The results suggest that relying solely on self-reports could mislead findings on drug use trends, recommending the inclusion of biological tests for more accurate assessments of drug exposure in clinical trials.