Publications by authors named "E Waldenlind"
Background: Cluster headache (CH) is a debilitating condition, but current therapies leave CH patients in pain. The extent of this problem in Sweden is unknown.
Methods: An anonymized questionnaire was sent to 479 Swedish CH patients to investigate patterns and perceived effects of treatments.
Article Synopsis
- - Up to 25% of individuals with cluster headache (CH) do not respond well to triptans, the usual first-line treatment, and this study examines the role of genetic variants and clinical characteristics in treatment response.
- - Researchers looked at five genetic variants in a Swedish cohort of 545 CH patients, finding that one variant (rs1024905) was significantly linked to not using triptans, alongside evidence that more 'effector' genetic variants corresponded with lower triptan use.
- - Clinical characteristics revealed that triptan users were more likely to trigger headaches with alcohol, experience autonomic symptoms, and be smokers when compared to non-users, suggesting that certain traits impact the likelihood of using triptans for
Background: Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep difficulties, though it is unknown whether this is a cause or a consequence of nightly headache attacks.
Objective: In this case-control study we have assessed sleep quality in study participants with CH in cluster bout respectively in remission, compared to a control group of neurologically healthy individuals to investigate the potential connection between sleep and CH.
Objective: The objective of this study was to aggregate data for the first genomewide association study meta-analysis of cluster headache, to identify genetic risk variants, and gain biological insights.
Methods: A total of 4,777 cases (3,348 men and 1,429 women) with clinically diagnosed cluster headache were recruited from 10 European and 1 East Asian cohorts. We first performed an inverse-variance genomewide association meta-analysis of 4,043 cases and 21,729 controls of European ancestry.
Patients diagnosed with the primary headache disorder known as cluster headache (CH) commonly report that their headache attacks occur in patterns of both circadian and seasonal rhythmicity. Vitamin D is essential for a variety of bodily functions and vitamin D levels are largely regulated by daylight exposure in connection with seasonal variation. For this Sweden-based study, the association between CH and three single-nucleotide polymorphisms in the vitamin D receptor gene, rs2228570, rs1544410, and rs731236, were investigated, as well as CH bouts and trigger factors in relation to seasonal and weather changes.
View Article and Find Full Text PDF