Doctor for a day: the impact of a health professions enrichment program on self-efficacy.

Introduction: Health profession enrichment programs for underrepresented minority students are crucial to supporting students' interest in healthcare careers and improving preparedness for important academic and professional milestones. Doctor for a Day, an enrichment program at the University of Washington School of Medicine, hosts monthly events where underrepresented kindergarten-12th grade students are exposed to careers in medicine by healthcare professionals from diverse backgrounds.

Methods: This study investigates to what extent participation in Doctor for a Day programming improves self-efficacy using a survey study of 958 students who attended at least one Doctor for a Day event between 2017 and 2023.

Characterizing Monoclonal Antibody Aggregation Using Charge Detection Mass Spectrometry and Industry Standard Methods.

Protein aggregation is a factor in a multitude of neurodegenerative diseases and aggregates of protein-based biotherapeutics can cause toxicity and adverse patient outcomes. Monoclonal antibody (M)-fluorophore (F) complexes with four different antibody sequences and masses of ∼680 kDa were analyzed using size-exclusion chromatography (SEC) and mass spectrometry using both quadrupole-time-of-flight (QTOF) and charge detection mass spectrometry (CDMS). Higher-order aggregates were not resolved using SEC, but species as large as the MF complex and MF were resolved using QTOF and CDMS, respectively.

Sharper minds: Feasibility and effectiveness of a mental health promotion package for university students targeting multiple health and self-care behaviours.

Objective: This study assessed the feasibility and effectiveness of the Sharper Minds package, a mental health intervention designed for university students, co-developed with student input. The program included a weekly self-monitoring e-tool and/or a short course targeting six self-care areas: physical activity, diet, sleep, music to aid study, mood regulation, and social connection.

Method: A non-randomised controlled trial involved 433 undergraduate students in three conditions: control, one-intervention (either e-tool or course), and two-intervention (both e-tool and course).

Electronic Excitation and High-Energy Reactions Originate from Anionic Microdroplets Formed by Electrospray or Pneumatic Nebulization.

Formation of energetic species at the surface of aqueous microdroplets, including abundant hydroxyl radicals, oxidation products, and ionized N2 and O2 gas, has been previously attributed to the high electric field at the droplet surface. Here, evidence for a new mechanism for electronic excitation involving electron emission from negatively charged water droplets is shown. Droplet evaporation can lead to emission of ions and droplet fission, but unlike positively charged droplets, negatively charged droplets can also shed charge by electron emission.

Playing for understanding: The impact of interactive gaming on young adults' sexual health education.

Objectives: This study examines the impact of a "choose your own adventure" (CYOA) game on improving understanding and facilitating discussions about dating, sex, and sexual health among immigrant and refugee youth who often face cultural and language barriers.

Study Design: A qualitative exploratory design was used to capture participants' experiences with the game.

Methods: Thirty-two immigrant and refugee youth aged 18-25 participated in semi-structured interviews.