Publications by authors named "E W Stein"
A mixed phenotype is characteristic of de novo Mixed Phenotype Acute Leukemia (MPAL) but can also be seen in other leukemias. It poses substantial classification and management dilemmas. Herein, we report a large cohort of acute leukemia with a mixed phenotype and define Acute Myeloid Leukemia with Mixed Phenotype (AML-MP) and MPAL as two distinct groups by characterizing the clinical, genetic, and transcriptomic features.
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- The study investigates the effectiveness of immunoadsorption (IA) treatment on post-COVID myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients, focusing on those with elevated β2 adrenergic autoantibodies.
- Patients underwent five IA sessions and showed significant improvement in physical functioning, fatigue, and other symptoms over six months, with 70% responding positively to the treatment.
- The findings suggest that IA could be a beneficial therapy for alleviating symptoms in post-COVID ME/CFS patients, indicating a possible link between autoimmunity and the condition.
Article Synopsis
- The study investigates CP symmetry violation in the decay of D^{+} particles into K^{-}K^{+}π^{+} using data from proton-proton collisions at a high energy of 13 TeV.
- A unique model-independent method was employed to analyze the phase-space distributions of D^{+} and D^{-} particles, correcting for any instrumental biases using D_{s}^{+} decays.
- The findings indicate no significant evidence of CP violation, with a p value of 8.1%, and measure specific CP asymmetry observables, marking this study as the most sensitive search of its kind in multibody decays.